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    Accepted for publication 9 March 2018 Published Volume 20 Pages 681—687 DOI https://doi.org/10.2147/IDR. S159455 Checked for plagiarism Yes Review by Single-blind Peer reviewers approved by Dr Andrew Yee Peer reviewer comments 4 Editor who approved publication: Dr Joachim Wink Department of Medicine, Chi Mei Medical Center, Tainan, Taiwan Background: The aim of this study was to investigate the genotypic differences between different sequence type MRSA isolates, especially focusing on silent mutations and the relationship between such mutations and ciprofloxacin resistance. Methods: Seventy-nine MRSA isolates were obtained for antibiotic susceptibility tests and molecular study. Results: Among these isolates, we found that the MIC474 silent mutation were found in community acquired-MRSA (CA-MRSA) isolates with susceptibility to most antibiotics, especially for ciprofloxacin and vice versa. Thus, this mutation may help to differentiate the different microbiologic characteristics of MRSA clinical isolates. Keywords: MRSA, silent mutation, This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https:// incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. Skin and Soft Tissue Infections prednisone and methylprednisolone MRSA Antibiotics Top 5 Treatments for Skin & Internal Infections MRSA Treatment, causes, and symptoms - Medical News Today
     
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