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Prednisone with tylenol - MedHelp Some Drugs Make Dementia Worse — ElderConsult Take Tylenol With Prednisone — Save Up To 80% - Lizone Caffeine is not known to interact negatively with the medication prednisone. However, this does not mean you won't have any adverse reactions while. xenical orlistat We would like to show you a description here but the site won’t allow us. Prednisone is quite tough on the digestive system though, so you should look to take it with some crackers or something so it doesn't mess with your stomach too much but the tylenol is safe to take while taking prednisone Take care.