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    Tamoxifen has rarely caused very serious (possibly fatal) strokes, blood clots in the lungs/legs, and cancer of the uterus. If you are taking tamoxifen to reduce the risk of breast cancer, or if your cancer is limited to the milk ducts (ductal carcinoma in situ-DCIS), then discuss the benefits and risks of taking this medication with your doctor. However, if you are taking tamoxifen to treat breast cancer, then the benefits of taking tamoxifen are greater than the risks of side effects. Get medical help right away if you develop symptoms of a stroke or blood clots in the lungs/legs, such as weakness on one side of the body, slurred speech, sudden vision changes, confusion, shortness of breath, chest pain, or calf pain/swelling. Tell your doctor right away if you develop symptoms of cancer of the uterus, such as unusual changes in your monthly period (e.g., amount or timing of bleeding), unusual vaginal discharge, or pain/pressure below your "belly button" (navel). Show More Tamoxifen is used to treat breast cancer. It is also used to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. Tamoxifen is designed to block estrogen receptors on the surface of breast cancer cells. In patients with Estrogen Receptor positive (ER ) disease, estrogen binds to these receptors and causes the breast cancer cells to grow and divide out of control. Tamoxifen blocks this signal and helps stop the breast cancer cells from growing. It can be taken by both pre-menopausal and post-menopausal women. Goals of therapy: Tamoxifen is commonly taken to decrease symptoms and prevent breast cancer from spreading to other parts of the body. Tamoxifen, when taken for metastatic breast cancer, is not commonly given with the goal of cure. In a multi-drug regimen, each medication has unique side effects.

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