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    Initialement la prémédication permettait de prévenir les effets secondaires liées au thiopental et aux premiers halogénés, en utilisant des parasympatholytiques. Puis elle a été intégrée à l’anésthesie balancée en administrant des morphiniques en préop. Ensuite est arrivé le concept de neuroleptanesthésie afin de potentialiser les drogues d’anesthésie. De nos jours , le but principal de la prémédication est l’anxiolyse. Actuellement sa place est discutée, du fait de l’utilisation de produits d’anesthésie puissants avec des durées d’action courte et peu d’effets secondaires ainsi que d’une prise en charge de la douleur multimodale et optimisée. Par ailleurs aucune étude de niveau de preuve suffisant n’existe pour justifier l’usage systématique de la prémédication anxiolytique. Je parle bien sur de patients naïfs pour les médicaments anxiolytiques, il est bien entendu recommandé de maintenir un traitement anxiolytique ou somnifère s’il est prescrit de manière chronique. By Tammy Preston, MS Brand Name: Catapres® (KAT-uh-press) Generic Name: clonidine (KLAHN-eh-deen) hydrochloride (HCL for short) Manufacturer: Boehringer Ingelheim Pharmaceuticals, Inc. Catapres® is the brand name for an anti-hypertensive medication FDA approved for the treatment of mild to moderate high blood pressure. Its generic equivalent is called clonidine hydrochloride. Although not FDA indicated for the treatment adult ADHD, Catapres® (clonidine hydrochloride) is generally well accepted as an alternative to the use of stimulants in treating adult ADHD. Catapres® Dosage Catapres® is available in doses of 0.1 mg (colored tan), 0.2 mg (colored orange) and 0.3 mg (colored peach). An extended-release trans-dermal skin patch, called Catapres-TSS® (the generic is called clonidine transdermal) is an alternative to taking the drug orally. A trans-dermal patch is medication in an adhesive patch that sticks to your skin and is slowly released into your system. This is a convenient delivery system that can be applied just once weekly.

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