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Detailed mechanism of action of Accutane is still unknown, but there are suggestions that its use decreases acne by reducing sebum production. depo calender Accutane (isotretinoin) is an acne medicine that quickly reached the U. market and become a best-settling prescription drug. Accutane drug was hailed by dermatologists as a breakthrough treatment for patients with severe acne. A number of generic equivalents of isotretinoin remain available today. It is still available in many countries outside of the United States. Within the United States, its generic form, isotretinoin, is available, and this drug is also marketed as under several different names within the United States: Claravis, Amnesteem, Sotret are a few of the best-known. Availability of generic Accutane (isotretinoin) available in many countries now and dominate the market. One of the most powerful treatments for severe cystic acne is a prescribed medicine called Isotretinoin. 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