It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Taking hydroxychloroquine and sulfasalazine together Hydroxychloroquine how long does it stay in body What happens if you double doses of plaquenil Aug 26, 2016 Left untreated, nephritis can lead to scarring and permanent damage to the kidneys and possibly end-stage renal disease ESRD. People with ESRD need regular filtering of their body’s waste done by a machine dialysis or a kidney transplant so that at least one kidney is working properly. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Sep 13, 2019 Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil kidney damage The Risk of Retinal Toxicity with Plaquenil, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Pregnancy hydroxychloroquine Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil Side Effects Common, Severe, Long Term -. Protective Effect of Hydroxychloroquine on Renal Damage in.. My understanding about Plaquenil is the doses taken for autoimmune disease is far less then that for Malaria, and even then the incident of neuropathy with malaria dosing is very low. I do know that eye damage from Plaquenil is extremely rare and most ophthalmologists tell me that they will never see a case.they still do bi-annual. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil is most known for its original purpose treating and preventing malaria. Malaria is a disease caused by parasites that can enter the body through a mosquito bite. The essential ingredient, known as quinine, is derived from the bark of the cinchona plant.