Zithromax Z-Pak is an antibiotic that fights bacteria. Zithromax Z-Pak is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Zithromax Z-Pak may also be used for purposes not listed in this medication guide. Zithromax Z-Pak is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Do not give this medicine to a child younger than 6 months old. Do not take this medicine in larger or smaller amounts or for longer than recommended. The dose and length of treatment with Zithromax Z-Pak may not be the same for every type of infection. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. Zithromax (azithromycin), also known as Z-Pak, is an antibiotic approved for treatment of respiratory, skin and other bacterial infections. Food and Drug Administration warned of an increased risk of cancer relapse and death in some patients who take the drug long-term. Studies link the drug to side effects, including an increased risk of fatal heart problems. Board-certified physicians medically review Drugwatch content to ensure its accuracy and quality. Drugwatch partners with Physicians’ Review Network Inc. PRN is a nationally recognized leader in providing independent medical reviews. Reviewer specialties include internal medicine, gastroenterology, oncology, orthopedic surgery and psychiatry. 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