Beta-blockers, which are normally used to treat hypertension (chronic high blood pressure), may also be prescribed to prevent migraines. There is a link between headaches and high blood pressure, but beta-blockers can prevent migraines even if you don't have hypertension. You and your doctor can decide whether you need to take a prophylactic migraine medication based on the frequency of your migraines, how long they last, how many migraine days you have per week or per month, and whether they improve with abortive treatment (treatment used at the time of an acute migraine attack). Generally, you might want to discuss migraine prevention with your doctor if you have more than four migraine days per month, especially if they do not improve quickly with treatment. Inderal (propranolol) is the beta-blocker that has been used and studied the most when it comes to migraine prevention. According to the United States Headache Consortium, there is evidence that propranolol can reduce the frequency of migraines. It is taken at a dose of 120 to 240 mg per day for migraine prevention. Propranolol in the management of recurrent migraine: a meta-analytic review. Nebivolol and metoprolol for treating migraine: an advance on β-blocker treatment? Pharmacologic management of acute attacks of migraine and prevention of migraine headache. Prophylaxis of migraine and mixed headache: a randomized controlled study. Fluoxetine for migraine prophylaxis: a double-blind trial. Divalproex sodium in migraine prophylaxis: a dose-controlled study [published correction appears in Cephalalgia. One study found that topiramate 100 mg daily had comparable efficacy to propranolol 160 mg daily; both drugs decreased monthly migraine frequency to 1.6 from a baseline of 4.9 with topiramate and 5.1 with propranolol (95% CI for the pair-wise difference of topiramate minus propranolol,-0.58 to 0.60).1. Propranolol in the management of recurrent migraine: a meta-analytic review. Buy citalopram 10mg online Buy xenical without consultation Lexapro 10 mg buy online Metformin 250 mg twice a day NHS medicines information on metoprolol - what it's used for, side effects. The main side effects of metoprolol are headaches, and feeling dizzy, sick or tired. Dec 9, 2015. CM is defined as a headache on ≥15 days per month for ≥3. Propranolol and metoprolol have the best evidence in migraine prophylaxis. Abrupt discontinuation of any beta-adrenergic-blocking agent, including metoprolol, can result in the development of myocardial ischemia, myocardial infarction, ventricular arrhythmias, or severe hypertension, particularly in patients with preexisting cardiac disease. Metoprolol can help reduce your symptoms if you have too much thyroid hormone in your body (thyrotoxicosis). You'll usually take it together with medicines to treat an overactive thyroid. This medicine comes as tablets and is only available on prescription. It's also given by injection, but this is usually done in hospital. Your doctor may advise you to take your first dose before bedtime because it could make you feel dizzy. If you don't feel dizzy after the first dose, take metoprolol in the morning. If you have metoprolol more than once a day, try to space the doses evenly throughout the day. Sufficient evidence and consensus exist to recommend propranolol, timolol, amitriptyline, divalproex, sodium valproate, and topiramate as first-line agents for migraine prevention. There is fair evidence of effectiveness with gabapentin and naproxen sodium. Botulinum toxin also has demonstrated fair effectiveness, but further studies are needed to define its role in migraine prevention. Limited evidence is available to support the use of candesartan, lisinopril, atenolol, metoprolol, nadolol, fluoxetine, magnesium, vitamin B (riboflavin), coenzyme Q10, and hormone therapy in migraine prevention. Data and expert opinion are mixed regarding some agents, such as verapamil and feverfew; these can be considered in migraine prevention when other medications cannot be used. Evidence supports the use of timed-release dihydroergotamine mesylate, but patients should be monitored closely for adverse effects. 2 Preventive therapy, which can reduce the frequency of migraines by 50 percent or more, is used by less than one half of persons with migraine headache.3Following appropriate management of acute migraine, patients should be evaluated for initiation of preventive therapy. Metoprolol for headache Common Side Effects of Lopressor Metoprolol Tartrate Drug., Evidence-Based Treatments for Adults with Migraine - Hindawi Fluconazole for yeastTamoxifen ukBuy clomid from usa A recent trial comparing metoprolol and nebivolol demonstrated a positive response—defined as a 50% reduction in headache frequency—to each drug at 14. What are the best prophylactic drugs for migraine? MDedge Family.. Metoprolol tartrate - Drug Summary - PDR. Net. Metoprolol Succinate Monograph for Professionals -. Metoprolol official prescribing information for healthcare professionals. Includes indications, dosage, adverse reactions, pharmacology and more. Abrupt cessation of therapy with a beta-blocker should be avoided especially in patients with ischaemic heart disease. When possible, metoprolol should be withdrawn gradually over a period of 10 days, the doses diminishing to 25mg for the last 6 days. Jan 1, 2006. A more recent article on migraine headache prophylaxis is available. metoprolol, nadolol, fluoxetine, magnesium, vitaminB2 riboflavin.