Tamoxifen therapy for breast cancer

Discussion in 'Rx Online' started by [email protected], 27-Aug-2019.

  1. DomSeo Moderator

    Tamoxifen therapy for breast cancer


    Tamoxifen, also known by the brand name Nolvadex, is one of the more commonly prescribed medications to prevent breast cancer recurrence, and when used appropriately, may reduce the risk of recurrence (of breast cancer coming back) by roughly 50 percent. The drug may also be used to reduce the chance that a woman will develop breast cancer in the first place, or to slow the growth of metastatic breast cancer. Tamoxifen works by binding to estrogen receptors on breast cells so that estrogen can't bind and stimulate growth. Learn about the potential side effects, how drug interactions may occur, and how tamoxifen differs from aromatase inhibitors. estrogen-like effects, depending on the particular type of tissue in the body where it acts. It is classified as a selective estrogen receptor modulator (SERM) along with the medication Evista (raloxifene). Tamoxifen is usually not considered beneficial for those who have estrogen or progesterone negative breast cancer. But they do know that some breast cancer cells are sensitive to estrogen. In order to fuel that growth, estrogen must attach itself to those breast cancer cells. Doctors think that tamoxifen stops estrogen from attaching to the cell. No estrogen means no growth for these types of breast cancer cells. Tamoxifen also keeps healthy breast cells from growing and multiplying. That way, it also reduces the number of cells that could become cancer. In a study of more than 13,000 women at high risk for breast cancer, scientists found that women who took tamoxifen for 5 years had fewer breast cancers than women who took a placebo. Newer research suggests that taking the drug for 10 years lowers the risk even more.

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    Tamoxifen is a hormone therapy drug used to treat ER+ breast cancer in pre- and post-menopausal women. Learn about how tamoxifen works and its side effects at Breast Cancer Care. Tamoxifen can significantly reduce the risk of recurrence of breast cancer after primary treatment with surgery, chemotherapy and/or radiation therapy. Like any medication, tamoxifen has risks and side effects and the benefits of treatment must be weighed against these risks. Tamoxifen is the most widely prescribed endocrine therapy for breast cancer, with more than 7.5 million woman-years of clinical experience.

    side effect of tamoxifen is blood clots, including deep vein thrombosis (DVT) and pulmonary embolus. In some cases, health care professionals may use the trade name Nolvadex when referring to the generic drug name tamoxifen. This medication is classified as an "anti-estrogen." (For more detail, see "How this drug works" section below). You should seek emergency help and notify your health care provider immediately if you develop sudden chest pain and shortness of breath. Notify your health care provider within 24 hours if you notice that one leg is swollen, red, painful and/or warm to touch and the other is not. A side effect of tamoxifen can be the development of uterine cancer. Women who have not had a hysterectomy should have regular pap smears and gyn examinations. Abnormal vaginal bleeding should be reported to your health care provider. Some types of breast cancer are affected by hormones in the blood. ER-positive and PR-positive breast cancer cells have receptors (proteins) that attach to estrogen, which helps them grow. There are different ways to stop estrogen from attaching to these receptors. Hormone therapy is a form of systemic therapy, meaning it reaches cancer cells almost anywhere in the body and not just in the breast. It's recommended for women with hormone receptor-positive (ER-positive and/or PR-positive) breast cancers, and it does not help women whose tumors are hormone receptor-negative (both ER- and PR-negative). Hormone therapy is often used after surgery (as adjuvant therapy) to help reduce the risk of the cancer coming back. Sometimes it is started before surgery (as neoadjuvant therapy) as well. Hormone therapy can also be used to treat cancer that has come back after treatment or that has spread to other parts of the body.

    Tamoxifen therapy for breast cancer

    Hormone Therapy for Breast Cancer Fact Sheet - National., Tamoxifen for Reducing Breast Cancer Recurrence

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  6. Tamoxifen Nolvadex, a hormone therapy drug, is used to treat breast cancers and to lower risk in women at high risk of breast cancer. Read about Tamoxifen.

    • Tamoxifen for Breast Cancer Treatment - Side Effects Susan G..
    • Risks and Benefits of Tamoxifen Therapy Cancer Network.
    • Tamoxifen Oral Uses, Side Effects, Interactions, Pictures, Warnings..

    Tamoxifen is the oldest of the hormonal therapies, drugs that block the effects of estrogen in the breast tissue. Tamoxifen is approved by the FDA to treat people diagnosed with both early-stage and advanced-stage hormone-receptor-positive breast cancer. Learn more about tamoxifen in pill form. A fact sheet that describes types of hormone therapy, its role in preventing and treating breast cancer, and possible side effects. Evaluates the role of longer duration therapy with tamoxifen in women who completed 5 years of tamoxifen, were cancer-free, and were.

     
  7. sibcom Moderator

    I have been given a couple of prescriptions but need to fill a couple more. One of them is for Sildenafil (aka Viagra) it's original intent was as a heart med- unfortunately it had the side effect that it does and so the prices are unbelievable. I need it to save my dog's life and can't afford it because of it's 'recreational' use. The heart specialist prescribed me with VIARGA (SILDENAFIL) 50MG Half tablet 2 times a day. 30 tablets are going to be over 0 and he is supposed to take 2-3 per day. He also advised me to continue all other med that I am taking. Feeling really worried & not sure if this diagnosis is realiable or shld I seek 2nd opinion ? Really feeling helpless & was always in tears when I go to bed every night now. It is an awkward one to get around though because its 2010 and life is a blur of work and getting to work and family and responsibility and money etc etc – you know the picture. Sildenafil Citrate Monograph for Professionals - Pharmacokinetics of Sildenafil after Single Oral Viagra Sildenafil Citrate Side Effects, Interactions.
     
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    Chlamydia is a sexually transmitted disease (STD) that affects both women and men. It is caused by a bacterial infection that is transmitted by having oral, anal, or vaginal sex with a person who already has chlamydia. Chlamydia is the most common sexually transmitted bacterial infection in the US, yet more than half of infected individuals exhibit no symptoms. Chlamydia rates continue to climb, too, with rates in California reaching the highest level on record in 2017. Chlamydia is curable, but requires antibiotics to clear the infection. Read more below to learn about specific treatment if you have chlamydia. It is common for someone with chlamydia to have no symptoms. How To Cure Chlamydia Health And Medicine Chlamydia - Diagnosis, Tests,Treatment, Medication - WebMD Azithromycin versus Doxycycline for Urogenital Chlamydia.
     
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