Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. How to get on hydroxychloroquine Hydroxychloroquine side effects high blood pressure Background/Purpose Hydroxychloroquine HCQ is a widely-used medication in many rheumatologic conditions. The most worrisome toxicity is irreversible damage to retinal pigment epithelium which can lead to blindness. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity1. According to these Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Pattern of Retinopathy Although the locus of toxic damage is parafoveal in many eyes, Asian. Purpose The 2016 guidelines by the American Academy of Ophthalmology AAO on screening for Hydroxychloroquine HCQ retinopathy HCQR recommend the use of ancillary testing, including Fundus. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil aao 2016 Retinal Physician - New Screening Guidelines for Hydroxychloroquine., Recommendations on Screening for Chloroquine and. Plaquenil et prise de poids December 10, 2016 Clinical Disease, Pharmacology The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. Ophthalmology Review. Detection of Hydroxychloroquine toxicity based on AAO 2016.. Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening. Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. Plaquenil and your eyes. A rare side effect of Plaquenil is damage to the eye's retina. The retina is the light-sensitive tissue at the back of the eye. Using Plaquenil for a long period of time may harm the retina, causing serious vision loss. People with retinal damage from Plaquenil are not aware at first that they are losing vision. Mar 10, 2017 The American Academy of Ophthalmology AAO in their 2016 recommendations defined ‘major risk factors’ on the basis of new data from a landmark epidemiological study of 2361 patients who had.