Metformin kidney

Discussion in 'Prescription Drugs Without Prior Prescription' started by BigDenny, 25-Aug-2019.

  1. usk5SpPK4223 New Member

    Metformin kidney


    Now, I have to deal with this sort of kidney pain and back pain everyday. I have been taking metformin for a week and have lost 19 pounds i am taking it for pcos and it has worked wonders i also have a normal cycle now i dont know if you have one or not but if you dont hopefully it will help I have been taking Metformn for over 3 years for my PCOS and never had an issue with kidney pain. I am on Synthoid, Metformin and Lovaza (basic Omega-3 acid to help lower triglycerides.) If the medication does not lower my level, should I ask the doctor to look at other underlining causes? Then when I got so sick had so many side effects I got scared that I might be doing damage to my already damaged liver. I have read that the metformin can cause liver and kidney damage so was worried about it, especially since my liver is damaged. I actually have had no problems at all taking it, I lost 50 lbs on it and stopped making cysts. my question to you is how much were you taking a day? I have taken Metformin 500 Mg x 2 times /day for nearly 3 years, but a year ago until now my feet are swollen, and I have bone spur on the left heel of my foot that is more growing bigger. Everyday when I take Metformin I usually have constipation and the top of my feet are swollen up. My fingers are so numb, and my urine is dark yellow and opaque. The results of the study indicated that the addition of metformin to peginterferon and ribavirin significantly decreased HOMA index at Week 24 and was associated with higher RVR rates vs placebo in these genotype 1 patients. Rarely, too much metformin can build up in the body and cause a serious (sometimes fatal) condition called lactic acidosis. Lactic acidosis is more likely if you are an older adult, if you have kidney or liver disease, dehydration, heart failure, heavy alcohol use, if you have surgery, if you have X-ray or scanning procedures that use iodinated contrast, or if you are using certain drugs. For some conditions, your doctor may tell you to stop taking this medication for a short time. Stop taking this medication and get medical help right away if you have any symptoms of lactic acidosis, such as unusual tiredness, dizziness, severe drowsiness, chills, blue/cold skin, muscle pain, fast/difficult breathing, slow/irregular heartbeat, or stomach pain with nausea/vomiting/diarrhea. Show More Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb. Read the Patient Information Leaflet if available from your pharmacist before you start taking metformin and each time you get a refill.

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    Font Size A A A Does Metformin Have Side Effects on Kidney. Provided by Expert Zhang Youkang on 2013-01-30. Metformin is commonly used to treat type 2 can help control blood sugar levels by increasing insulin sensitivity, decreasing sugar production by the liver and decreasing sugar absorption. Metformin previously had been contraindicated for patients with renal disease or dysfunction, as suggested by serum creatinine levels at or above 1.5 mg/dL for men and 1.4 mg/dL for women or. Metformin has traditionally been regarded as contraindicated in chronic kidney disease CKD, though guidelines in recent years have been relaxed to permit therapy if the glomerular filtration rate GFR is 30 mL/min. The main problem is the perceived risk of lactic acidosis LA.

    Metformin does not damage kidneys, that damage is done by high blood sugars. The biggest concern is when metformin is used and it doesn't adequately control blood sugars. In such case other medications or insulin should be started to get good blood sugar control. I have read that the metformin can cause liver and kidney damage so was worried about it, especially since my liver is damaged. The sooner blood sugars can be under tight control the better, as far as preventing / healing damage. Then when I got so sick had so many side effects I got scared that I might be doing damage to my already damaged liver. I have been taking metformin for a week and have lost 19 pounds i am taking it for pcos and it has worked wonders i also have a normal cycle now i dont know if you have one or not but if you dont hopefully it will help Metformin has been known to cause kidney and liver problems, but this does not happen in all patients, and there is some evidence there is a co-factor, in development of damage, such as alcoholism, or a combination of other drugs. All in all, the drug has a relatively good safety record. I would not fear taking Metformin if your physician recommends or concurs with your suggestion. I have taken Metformin 500 Mg x 2 times /day for nearly 3 years, but a year ago until now my feet are swollen, and I have bone spur on the left heel of my foot that is more growing bigger. Everyday when I take Metformin I usually have constipation and the top of my feet are swollen up. Metformin has actually brought a “black box” warning on its label — mandated by the U. Food and Drug Administration (FDA) — ever since it became available in the United States in 1994, due to concerns about lactic acidosis. This unusual however very serious response was found to be an unacceptably typical side effect of a drug associated to metformin — phenformin — which was pulled from the United States market in 1977. Lactic acidosis is much more typical in people with impaired kidney function. Since metformin’s warning label is based, in part, on issues about a various drug entirely, many scientists have actually attempted to approximate how safe metformin is for people with diabetes whose kidney function suffers. In 2015, we kept in mind that numerous researchers believe metformin is safe for individuals with mild to moderate kidney disease, defined as having an estimated glomerular purification rate (e GFR) of 30 — 60 ml/min. And one study found that using a safety cutoff of an e GFR of 30 ml/min, almost one million individuals in the United States who currently do not take metformin due to the fact that of the FDA’s labeling may be able to securely do so. The proof, it seems, has just grown more powerful in favor of metformin being more extensively prescribed to people with kidney disease. As kept in mind in a current post at Diabetes In Control.com, the blood-glucose-lowering advantages of loosening up limitations on metformin could be huge.

    Metformin kidney

    Can Metformin Increase Risk of Kidney Disease? - Type 2 Nation, FDA Metformin Safe for Some Patients With Renal Problems

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  5. Treatment with metformin appears to be safe and efficacious in patients with type 2 diabetes and moderate to severe chronic kidney disease.

    • Metformin Safe in T2D With Moderate to Severe Chronic Kidney..
    • Metformin in Chronic Kidney Disease Time for a Rethink.
    • Metformin safe in patients with mild, moderate chronic kidney disease.

    Metformin is an oral diabetes medicine that helps control blood sugar levels. Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Metformin-associated lactic acidosis is exceedingly rare based on the available literature, and even though the use of metformin has not been comprehensively assessed in individuals with CKD, there is extensive evidence that this agent often is used without adverse effects in those with mildly to moderately reduced renal function. Despite warnings, many doctors are already prescribing metformin to patients with kidney disease, the study published in the Dec. 24/31 issue of the Journal of the American Medical Association revealed. "Many in the field know that metformin can be used cautiously in patients who have mild to moderate kidney problems," Inzucchi said.

     
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