Metoprolol and sleep

Discussion in 'Prescription Drugs Canada' started by Potas, 11-Sep-2019.

  1. piin Moderator

    Metoprolol and sleep


    Sleep is an innate and essential part of human life. Various aspects of sleep are negatively affected by beta-blockers. We compared the impact of two beta-blockers, metoprolol succinate (extended release) and nebivolol, on sleep quality in patients with stage 1 hypertension. This was a prospective, randomized, open-label, parallel-group study. Eligible patients were administered the Pittsburgh Sleep Quality Index (PSQI) questionnaire by a blinded interviewer and were randomized to receive metoprolol (starting dose 25 mg) or nebivolol (starting dose 2.5 mg) once daily for 6 weeks. The first dose was administered before patients left the clinic. Visits were scheduled for 1, 2, 4, and 6 weeks after the initiation of therapy. You should not use this medication if you have a serious heart problem (heart block, sick sinus syndrome, slow heart rate), severe circulation problems, severe heart failure, or a history of slow heart beats that caused fainting. Metoprolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins). Metoprolol is used to treat angina (chest pain) and hypertension (high blood pressure). Metoprolol may also be used for other purposes not listed in this medication guide. You should not use this medication if you are allergic to metoprolol, or other beta-blockers (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others), or if you have: Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. If you are being treated for high blood pressure, keep using this medication even if you feel well. You may need to use blood pressure medication for the rest of your life. Other drugs may interact with metoprolol, including prescription and over-the-counter medicines, vitamins, and herbal products. Do not take this medicine in larger or smaller amounts or for longer than recommended. While using metoprolol, you may need frequent blood tests at your doctor's office. If you need surgery, tell the surgeon ahead of time that you are using metoprolol. Not all possible interactions are listed in this medication guide. Every effort has been made to ensure that the information provided by Cerner Multum, Inc.

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    Brand Lopressor, Metoprolol Succinate ER, Metoprolol Tartrate, Toprol-XL. asthma, chronic obstructive pulmonary disease COPD, sleep apnea, or other. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Lopressor metoprolol tartrate Tablets and Injection is a selective beta-adrenoreceptor blocking agent beta-blocker used to treat high blood presure hypertension, angina, and heart attacks. Lopressor is available as a generic. Common side effects of Lopressor include

    Food can enhance the levels of metoprolol in your body. You should take metoprolol at the same time each day, preferably with or immediately following meals. This will make it easier for your body to absorb the medication. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking metoprolol. Metoprolol is only part of a complete program of treatment that also includes diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely. Switch to professional interaction data Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Added : I just recently started taking my 50mg dose at night like my MD recommended and then monitor my BP and HR during the day to make sure its still effective in keeping them within normal ranges. Added : The medications I take in the morning are lexapro 20mg and Vyvanse 60mg. metoprolol adds to the CNS effects of psych meds, so I agree that you should try taking it at night. Matter of fact, before bed may actually help you get to sleep better. Now, you may want to consider that some folks experience urinary incontinence with metoprolol and if you have a tendency to have to go at night more than during the day, this may be something to watch as you try it out. God bless you, please let me know if I could be of any assistance? I take it also, as needed, for back pain and I notice that if I take it a couple of days in a row, I start getting that last minute urge/now it's too late kind of thing that goes away when I have a break in dosing. I used to take 100mg SR at night, my doctor now has prescribed me to take it once in the morning too - Metoproplol 100mg SR capsules. So if I switch to taking the metoprolol which is the extended release version at night rather than with my anti-depressants and vyvanse in the morning, will it still be effective in controlling my BP and Tachycardia symptoms during the day as well. I guess the only way to know for sure is to take my vitals throughout the day to see. jbacon - I am interested in hearing a bit about your experience.

    Metoprolol and sleep

    Beta-blockers and sleep a controlled trial., Metoprolol Oral Route Side Effects - Mayo Clinic

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  6. Metoprolol Lopressor, Toprol XL is a prescription drug used to treat high blood pressure, angina, abnormal rhythms of the heart, and some neurological conditions. Side effects include low blood pressure, dreaming, diarrhea, abdominal cramps, and sore throat. Drug interactions, dosage, and pregnancy and breastfeeding safety information are provided.

    • Metoprolol Lopressor, Toprol XL Side Effects & Dosage.
    • Common Side Effects of Lopressor Metoprolol Tartrate..
    • Metoprolol Reviews Everyday Health.

    Metoprolol adds to the CNS effects of psych meds, so I agree that you. Matter of fact, before bed may actually help you get to sleep better. Nov 2, 2017. Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic. Feb 28, 2018. What is metoprolol? What are Metoprolol side effects? Who should avoid Metoprolol? Click here to learn more about this beta blocker.

     
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    Immediate-release: Decrease initial dose to 0.25 mg PO q8-12hr; may gradually increase if necessary and as tolerated; may increase every 3-4 days by ≤1 mg/day to 5-6 mg/day average dose Extended-release: Start at 0.5 mg PO q Day; may gradually increase if necessary and as tolerated; may increase q3-4Days by ≤1 mg/day to 3-6 mg/day Use smallest effective dose to avoid ataxia and oversedation Elderly especially sensitive to benzodiazepine effects; higher plasma levels exhibited because of reduced clearance Mean half-life: 16.3 hours in healthy elderly individuals (range: 9-26.9 hr), compared with 11 hours in healthy adults (range: 6.3-15.8 hr) Drowsiness (77%) Impaired coordination (40-50%) Increased appetite (30-35%) Fatigue (30-35%) Memory impairment (30-35%) Irritability (30-35%) Decreased salivation (30-35%) Cognitive disorders (20-30%) Insomnia (20-30%) Dcreased appetite (20-30%) Headache (20-30%) Lightheadedness (20-30%) Dysarthria (20-30%) Diarrhea, constipation, and nausea/vomiting (20-30%) Weight change (20-30%) Nasal congestion (15-20%) Decreased or increased libido (10-15%) Menstrual disorder (10-15%) Difficult micturition (10-15%) Tachycardia (5-10%) Confusion (5-10%) Insomnia (5-10%) Nausea/vomiting (5-10%) Blurred vision (5-10%) Nasal congestion (5-10%) Hypotension (1-5%) Syncope (1-5%) Akathisia (1-5%) Dizziness (1-5%) Increased salivation (1-5%) Nervousness (1-5%) Tremor (1-5%) Weight change (1-5%) Gastrointestinal: Liver enzyme elevations, hepatitis, hepatic failure CNS: Hypomania, mania Immunologic: Stevens-Johnson syndrome, angioedema, peripheral edema Endocrine: Hyperprolactinemia, gynecomastia, galactorrhea Concomitant use of benzodiazepines and opioids may result in profound respiratory depression, coma, and death; administer concomitantly when there are no alternative options; limit dosages and durations to minimum required; monitor for signs and symptoms of respiratory depression and sedation 10 days) Do not stop treatment abruptly; slowly taper to discontinuation (0.5 mg q3Days) Use caution in elderly patients Use caution in debilitated patients Use caution in severe respiratory depression Use caution in patients who recently received other respiratory depressants Use caution in patients who are at risk of falls May have prolonged effects in obese patients when discontinued; use caution Not for us in acute alcohol intoxication Use with caution in patients with hepatic or renal impairment Myasthenia gravis (allowable in limited circumstances) Use caution in cases of respiratory disease (COPD), sleep apnea, renal/hepatic disease, open-angle glaucoma (questionable), depression, suicide ideation, drug abuse CNS depressant; may impair ability to perform hazardous tasks Paradoxical reactions, including hyperactive or aggressive behavior reported Cigarette smoking may decrease alprazolam concentration up to 50% Mania and hypomania episodes reported in depressed patients Pregnancy category: D Lactation: Enters breast milk/not recommended Minor tranquilizers should be avoided in first trimester of pregnancy due to increased risk of congenital malformations Maternal use shortly before delivery is associated with floppy infant syndrome (good and consistent evidence) Prenatal benzodiazepine exposure slightly increases oral cleft risk (limited or inconsistent evidence) Binds receptors at several sites within the CNS, including the limbic system and reticular formation; effects may be mediated through GABA receptor system; increase in neuronal membrane permeability to chloride ions enhances the inhibitory effects of GABA; the shift in chloride ions causes hyperpolarization (less excitability) and stabilization of the neuronal membrane The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Long-Term Effects of Xanax - Solutions Recovery Xanax, Niravam alprazolam dosing, indications, interactions. This Is Your Body on Xanax - VICE
     
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