Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Treatment of plaquenil hyperpigmentation Chloroquine aralen drug card Aralen 150 mg Chloroquine intercalating dna HYDROQUINONE USP, 4% SKIN BLEACHING CREAM is indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines, and other unwanted areas of melanin hyperpigmentation. Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Common side effects include vomiting, headache, changes in vision and muscle weakness. Severe side effects may include allergic reactions. It does not appear to be safe during Hydroxychloroquine-associated hyperpigmentation with gray to black discoloration. Mucocutaneous hyperpigmentation because of anti-malarial therapy has been reported since World War II 2 ; however, HCQ-associated hyperpigmentation seems to be less common than with other antimalarials such as chloroquine 3, 4. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine hyperpigmentation Cutaneous hyperpigmentation during therapy with., Hydroxychloroquine - Wikipedia Can i take ginsing of i'm am on plaquenilCan plaquenil cause yeast infectionsChloroquine malaria tablets bootsAralen malaria prevention Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. Hydroxychloroquine DermNet NZ. Hydroxychloroquine-induced Hyperpigmentation of the Skin.. Hydroxychloroquine‐induced hyperpigmentation the staining.. Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Hydroxychloroquine-Induced Hyperpigmentation. From the Departments of *Rheumatology and †Dermatology, Walter Reed National Military Medical Center; and ‡Uniformed Services University of the Health Sciences, Bethesda, MD. No financial support was received for this study. The authors declare no conflict of interest. Objective To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Design, Setting, and Participants In a case-control study conducted at a French referral center for SLE and antiphospholipid syndrome, 24 patients with SLE.