Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Is plaquenil immunosuppressive Hydroxychloroquine neuropathy Changes to the menstrual cycle don't appear to be listed as a known side-effect of hydroxychloroquine, but that doesn't necessarily mean that it couldn't be involved. It may be worth discussing with your doctor. Children should not take hydroxychloroquine for long-term therapy. Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to hydroxychloroquine. If you are taking hydroxychloroquine for a long period of time, your doctor will recommend frequent eye exams. Hydroxychloroquine treats malaria, systemic lupus erythematosus, rheumatic disorders like rheumatoid arthritis, porphyria cutanea tarda, and Q fever. 1 In 2014, its efficacy to treat Sjögren syndrome was questioned in a double-blind study involving 120 patients over a 48-week period. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine and menstrual cycle Periods and plaquenil Lupus Forums at The Lupus Site, Hydroxychloroquine MedlinePlus Drug Information Plaquenil aravaZ 038 is this hydroxychloroquine Heavy or prolong menstrual bleeding is found among people who take Plaquenil, especially for people who are 40-49 old, have been taking the drug for 5 - 10 years, also take medication Humira, and have Osteoporosis Plaquenil and Heavy or prolong menstrual bleeding - from.. Hydroxychloroquine - Wikipedia. Plaquenil Withdrawal – Life As An Anomaly. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARDregulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Re Hydroxychloroquine and menstruation Reply #2 on July 30, 2013, AM Hi SueLaw - yeah I have noticed a change in my cycle since starting on plaquenil in January - but I was wondering if it was my old age of 45 and things starting to change or if it a combination of plaquenil and the age thing. Your menstrual cycle is part of your body’s way of preparing for a possible pregnancy each month. Understanding how the process works is important, since you can use this information to help to either get pregnant or avoid getting pregnant, to better manage any menstrual symptoms you are experiencing, and understand when there might be a problem.