While the mechanism is poorly understood, pregnant women have a reduced immune response and therefore less effectively clear malaria infections. In addition, malaria parasites sequester and replicate in the placenta. Can plaquenil cause psoriatic arthritis Chloroquine sulfa allergy Chloroquine phosphate for malaria Plaquenil to treat skin rash The teratogenic effect is thought to involve red blood cells production, erythropoiesis, which implies the human sensitive period would be within the first trimester of pregnancy. An effect of ACTs on early pregnancy loss will be difficult to detect, especially in communities where artemisinins are likely to be used most frequently. Malaria during pregnancy has adverse effects, including maternal mortality, miscarriage, and low birthweight. During early pregnancy, treatment options are limited, especially in regions with drug resistance. In a retrospective study covering a 25-year period 1986–2010. Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best. Malaria infection during pregnancy can lead to miscarriage, premature delivery, low birth weight, congenital infection, and/or perinatal death. Pregnant women are three times more likely to develop severe disease than non-pregnant women acquiring infections from the same area. Effect of chloroquine injection on early pregnancy Chloroquine and premature evacuation of uterine conceptus., First-Trimester Malaria Treatment and Outcomes Plaquenil urticarial vasculitisCan plaquenil cause ankle swellingGeneric plaquenil gg 620Benefits of taking plaquenilChloroquine g6pd If you use other drugs or over the counter products at the same time, the effects of Chloroquine Injection may change. This may increase your risk for side-effects or cause your drug not to work properly. Chloroquine Injection - Uses, Side-effects, Reviews, and Precautions.. Effects of chloroquine on viral infections an old drug.. The effects of quinine and chloroquine antimalarial.. Chloroquine has a schizonticidal effect and kills the erythrocytic forms of malaria parasites at all stages of development, but does not affect the sporozoites inoculated by the mosquito or the malaria parasite in human liver cells. Find patient medical information for Chloroquine Injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Pregnancy Family & Pregnancy. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite.