It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Quinacrine chloroquine antimalarial Generic plaquenil manufacturers Hydroxychloroquine tests Most people say about 6 months. It works over time. It's pretty suttle. One day all the sudden you will notice that your arms or legs or feet don't feel as bad as they used to. Not that it is a cure all but it usually does help. To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. One day I was congratulating myself for getting so many things done and I realised that the days had been getting better without my noticing. In the beginning I also was on a low dose of prednisone, which helped until plaquenil kicked in. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long does it take plaquenil to start working RA and Hydroxychloroquine How Effective is it for Rheumatoid., Plaquenil Uses, Dosage & Side Effects - Plaquenil and mctdHow much is plaquenil without insuranceWhat happens when you quit taking plaquenilPlaquenil and sulfa allergy Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Stopping plaquenil. DailyStrength. How long did Plaquenil/Hydroxychloroquine take.. How long until Hydroxychloroquine takes effect - LUPUS UK. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects even if it doesn't seem to be working at first even when your symptoms improve to help keep the disease under control. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. I'm back on it and waiting the 3-4 months it takes to work at least that's how long it took the first time. I have a great opthamologist who has assured me he will catch retinal damage before I will ever notice a change in my vision, so as far as I'm concerned, I want to stay on Plaquenil until I'm forced off it.