Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Effect of chloroquine on liver enzymes Allergy reaction to plaquenil Acute chloroquine toxicity Cutaneous lupus erythematosus CLE is an autoimmune, inflammatory skin disease seen in patients with or without systemic lupus erythematosus SLE. The management of CLE includes treatment and prevention of lesions, as well as routine assessment for systemic disease. Treatment options include both topical and systemic therapies. The treatment of cutaneous lupus erythematosus is centered upon formulating a regimen of topical and systemic therapies designed to reduce disease activity and minimize cosmetic damage. Sun avoidance and sunscreen are important preventative measures proven to minimize cutaneous lupus erythematosus exacerbations. User Reviews for Plaquenil to treat Systemic Lupus Erythematosus. The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Treatment of discoid lupus erythematosus with chloroquine Hydroxychloroquine Uses, Dosage & Side Effects -, Treatment of Cutaneous Lupus Erythematosus Plaquenil sweets syndromePlaquenil for lyme treatment Treatment of discoid lupus erythematosus Begin treatment with the elimination of foci of chronic infection in the body, the normalization of endocrine disorders. Eliminate other irritating and provoking factors, such as direct sunlight, radiation therapy, cold, drafts, external skin damage. Discoid lupus erythematosus Symptoms and treatment of.. Plaquenil User Reviews for Systemic Lupus Erythematosus at.. Chronic Discoid Lupus Erythematosus — Treatment with Daraprim.. Since the initial success of the treatment of lupus erythematosus with quinacrine Atabrine by Prokoptchouk 1a and Popoff and Kutinscheff 1b and later by Page, 2 in Europe, attempts have been made to find other less toxic antimalarial agents. Discoid lupus erythematosus DLE is a form of lupus that mainly affects your skin. DLE is different from systemic lupus erythematosus SLE, the most common form of lupus, which can affect any part of the body. Aug 30, 2017 Discoid lupus discoid lupus erythematosus is a chronic autoimmune disease affecting the skin. It gets its name from the coin-shaped lesions it produces. This condition causes a severe rash that.