Plaquenil maculopathy visual field

Discussion in 'Health Canada Drug Database' started by Frank007, 04-Mar-2020.

  1. nml New Member

    Plaquenil maculopathy visual field


    Newer studies have preferred practice protocols be changed to using spectral-domain OCT technology as the main screening device for detection of early retinal changes in plaquenil toxicity. The patient reported that she was in reasonably good health despite a long-term history of lupus.

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    Visual field tests take a long time to complete and can be difficult for patients. A traditional 10-2 test takes at least 15 minutes per eye, and if a 24-2 is added, a patient is taking the tests. History of Present IllnessOcular ExaminationDiscussionFull Clinical History and CourseDifferential Diagnosis Visual field abnormalities occurred in 35 patients. Five patients developed hydroxychloroquine ocular adverse effects, of which 4 were visual field defects and 1 was significant vortex keratopathy. None of these patients developed visual symptoms, changes in visual acuity, or fundus abnormalities resulting from drug toxic effects nor did they.

    In addition to medication for her lupus, she was also being treated with glyburide for diabetes and an unkown medication for hypertension. She was taking 200 milligrams of plaquenil per day to treat her lupus and had been on this dose level for the past twenty years.

    Plaquenil maculopathy visual field

    Protecting your eyesight when taking Plaquenil Lupus., Hydroxychloroquine Plaquenil Toxicity and.

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  4. Upon the detection of the visual field defects, the hydroxychloroquine was stopped. She was taking hydroxychloroquine 5.0 mg/kg/day with a duration of 10 years with a cumulative dose of 1460g putting her at increased risk for hydroxychloroquine retinal toxicity.

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    Multifocal electroretinography mfERG, spectral domain optical coherence tomography SD-OCT, and fundus autofluorescence FAF add sensitive objective data that can confirm suspicions from a borderline visual field or show anatomic damage before there is any visible “classic” bull's eye retinopathy.2, 3 Recent recommendations from the American Academy of Ophthalmology AAO emphasized the importance of adding objective tests and the rationale for recognizing this toxicity early to. Side effectsManagementGoalsMechanismPrognosisPathophysiologyToxicityPreventionInteractionsGeneticsPurposeMedical usesAnalysisResearchDiagnosisSecurityResourcesContraindications To analyze Humphrey visual field HVF findings in hydroxychloroquine HCQ retinal toxicity. HVF tests were interpreted retrospectively in this

     
  5. slipper Guest

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  6. GtW Moderator

    Stopping Plaquenil - General Discussion - Life With Lupus I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it.

    Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus
     
  7. toykriss Well-Known Member

    Prescription Medications That Can Affect Age-Related. Patients often ask if their medications affect the risk of vision loss from age-related macular degeneration AMD. One class of medications can lead to more severe vision loss in people with the wet form of the disease, and another class of drugs may have a beneficial effect.

    Pause the Plaquenil?