Nobody has told me any different and when I was going out to work every morning I didn't have time to mess about so took all my tabs the same time. But if you want confirmation then speak to the pharmacist or your gp. Omeprazole (Prilosec), Nexium, and other proton pump inhibitor drugs can be affected by taking supplements, and can affect your ability to absorb certain vitamins and minerals. John's wort, for example, should not be taken with these drugs. Does plaquenil cause low wbc Plaquenil sleepy Hydroxychloroquine prescribing information CYP2D6 inhibitors, such as hydroxychloroquine, could theoretically impair propranolol metabolism; the clinical significance of such interactions is unknown. Hydrocodone Moderate Concomitant use of hydrocodone with hydroxychloroquine may increase hydrocodone plasma concentrations and prolong opioid adverse reactions, including hypotension, respiratory depression, profound sedation, coma, and death. Prilosec omeprazole may increase the amount of some statins present in the blood and may also increase the side effects of statins. Tagamet cimetidine may increase the amount of some statins present in the blood and may also increase the side effects of statins. Possible food and drug interactions when taking Plaquenil If Plaquenil is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Plaquenil with the following Any medication that may cause liver damage Aurothioglucose Solganal Be sure to also read about magnesium depletion which can occur with these drugs in the Magnesium Supplements Review. These interactions are explained in the Proton Pump Inhibitors article, which is part of the extensive Drug Interactions section of our website (where you can look up interaction for other drugs you may be taking). Prilosec and plaquenil interactions Diltiazem Oral Interactions with Other Medication, Be Aware of These Statin Drug Interactions Is plaquenil addictive As far as I've been able to find out, the only antacid that may cause an interaction with Plaquenil is one that contains magnesium, and the same caution applies to magnesium based laxatives and magnesium supplements. PPIs Losec and the likemay interfer with absorption of many drugs and nutrients, though. Plaquenil and antacids?. Plaquenil & other drug interactions ? Lupus Forums at The.. Supplement Interactions With Proton Pump Inhibitors PPIs. Appendix 16Table of drug interactions. This appendix provides a table of drug interactions with medications used in other conditions. The British National Formulary BNF includes a summary appendix dedicated to drug interactions. More detailed information can be found in Stockley's Drug Interactions Baxter, 2008. Prilosec is the brand name of the drug omeprazole, which is used to treat symptoms of gastroesophageal reflux disease GERD. GERD happens when acid from the stomach flows backward into the. Omeprazole is in a class of drugs known as proton pump inhibitors that decrease stomach acid. Known as Prilosec in its over-the-counter form, omeprazole is prescribed for acid reflux disease, heartburn and stomach ulcers.