Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine clinical trial cancer Chloroquine action With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage. Certain people are more susceptible than others to potential vision problems with Plaquenil. Once again, vision changes linked to Plaquenil are rare, but certain people are at higher risk of developing the problem. High-risk patients would include those who I've been on plaquenil since 2011 and I haven't had any issues like that with it. Not even any unusual dreams. I do get sleep paralysis on very rare occasions, but that started well before the plaquenil, and I've only had one incident since. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil sleep problems HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical., Taking Plaquenil for Rheumatoid Arthritis Plaquenil makes me sleepyLichen sclerosus plaquenilHow longbto take plaquenil after alcohol Been off of plaquenil for about 5 months and I can tell difference of my sleep. I sleep more hours during those periods I stop taking plaquenil. Now, that I am back taking plaquenil I could hardly sleep. I think I just sleep 2 hours or less or a little bit more than 2 hours each night. Does anyone. Insomnia because of plaquenil DailyStrength. Hydroxychloroquine/plaquenil and sleepwalking lupus. Plaquenil Side Effects Common, Severe, Long Term -. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Jan 25, 2012 Regular plaquenil eye exams should quell concerns about eye complications, which are very rare. I was advised to take it at bed time, so I would sleep through any other side effects it might cause me, but I never noticed any side effects at all -- except feeling a lot better, less fatigue, less joint pain, and fewer issues overall. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis.