Viagra classification

Discussion in 'Drugs Online' started by turkdom, 12-Sep-2019.

  1. fetis Guest

    Viagra classification


    Sildenafil is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, c GMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased c GMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH. However, patient may take drug 30 minutes to 4 hours before sexual activity. as a single dose, p.r.n., 1 hour before sexual activity. Based on effectiveness and tolerance by patient, may increase dose to maximum single dose of 100 mg or decrease dose to 25 mg. A maximum recommended dosing frequency is once daily. Erectile action: Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cyclic guanosine monophosphate (c GMP) in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of c GMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Absorption: Rapidly absorbed after oral administration. A high-fat meal delays the rate of absorption by about 1 hour and reduces peak levels by one-third.

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    In a pilot study, sildenafil 25 mg PO once daily at night combined with alfuzosin 10 mg PO once daily after the same meal proved to be more effective than. Viagra is the trade name of sildenafil, an anti-impotence drug, belonging to a new group of drugs known as phosphodiesterase type 5 PDE5 inhibitors. VIAGRA prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects.

    Viagra is the trade name of sildenafil, an anti-impotence drug, belonging to a new group of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Developed originally as a treatment for angina, patients prescribed with Viagra reported erections as an unexpected side effect. As an inhibitor, the drug works by improving the blood flow to the penis by stopping the degradation of cyclic guanosine monophosphate (c GMP) – a chemical released during sexual stimulation which relaxes the smooth muscle in the penis. Once these muscles have been relaxed, blood vessels are able to dilate, allowing the blood flow to the penis to increase. By selectively inhibiting the breakdown of c GMP, Viagra uniquely promotes the flow of blood into the penis at times of sexual stimulation, therefore facilitating an erection, though not causing one. Viagra therefore does not increase sexual desire (although a side effect may be an increase in confidence which in turn may increase sexual desire). It follows also that those who do not suffer from impotence caused by insufficient blood flow may gain little from taking the drug. The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for men with diabetes mellitus. Rare but serious adverse effects found through postmarketing surveillance include prolonged erections, severe low blood pressure, myocardial infarction (heart attack), ventricular arrhythmias, stroke, increased intraocular pressure, and sudden hearing loss. Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection. Protease inhibitors inhibit the metabolism of sildenafil, effectively multiplying the plasma levels of sildenafil, increasing the incidence and severity of side effects. Those using protease inhibitors are recommended to limit their use of sildenafil to no more than one 25 mg dose every 48 hours. blocker (typically prescribed for hypertension or for urologic conditions, such as benign prostatic hypertrophy) at the same time may lead to low blood pressure, but this effect does not occur if they are taken at least 4 hours apart.

    Viagra classification

    European Medicines Agency - Human medicines - Viagra, Viagra – DrugWise

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  4. Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. It is unclear if it is.

    • Sildenafil - Wikipedia.
    • VIAGRA Dosage & Rx Info Uses, Side Effects -.
    • Sildenafil DB00203 - Sildenafil - DrugBank.

    Classification of Viagra 50 mg, in the treatment of male erectile dysfunction. the effect of the change of the classification on the magnitude of the incorrect use. Dec 28, 2018. Viagra sildenafil is used to treat erectile dysfunction or impotence in men. Includes Viagra side effects, interactions and indications. Jan 15, 2018. Sildenafil Viagra is used to treat erectile dysfunction impotence; inability to get or keep an erection in men. Sildenafil Revatio is used to.

     
  5. SanyaK New Member

    While once a first-line treatment for hypertension, the role for beta blockers was downgraded in June 2006 in the United Kingdom to fourth-line, as they do not perform as well as other drugs, particularly in the elderly, and evidence is increasing that the most frequently used beta blockers at usual doses carry an unacceptable risk of provoking type 2 diabetes. Propranolol is not recommended for the treatment of hypertension by the Eighth Joint National Committee (JNC 8) because a higher rate of the primary composite outcome of cardiovascular death, myocardial infarction, or stroke compared to an angiotensin receptor blocker was noted in one study. Propranolol works to inhibit the actions of norepinephrine, a neurotransmitter that enhances memory consolidation. In one small study individuals given propranolol immediately after trauma experienced fewer stress-related symptoms and lower rates of PTSD than respective control groups who did not receive the drug. Due to the fact that memories and their emotional content are reconsolidated in the hours after they are recalled/re-experienced, propranolol can also diminish the emotional impact of already formed memories; for this reason, it is also being studied in the treatment of specific phobias, such as arachnophobia, dental fear, and social phobia. Ethical and legal questions have been raised surrounding the use of propranolol-based medications for use as a "memory damper", including: altering memory-recalled evidence during an investigation, modifying behavioral response to past (albeit traumatic) experiences, the regulation of these drugs, and others. However, Hall and Carter have argued that many such objections are "based on wildly exaggerated and unrealistic scenarios that ignore the limited action of propranolol in affecting memory, underplay the debilitating impact that PTSD has on those who suffer from it, and fail to acknowledge the extent to which drugs like alcohol are already used for this purpose." Propranolol may be used to treat severe infantile hemangiomas (IHs). Propranolol User Reviews for Anxiety at Propranolol PIM 441 - Propranolol dosage instructions - uk
     
  6. vrons1 User

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  7. bipOpisicTriz XenForo Moderator

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