Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil help arthritis Hydroxychloroquine related rash on external genitalia Stevens-Johnson syndrome requires hospitalization, often in an intensive care unit or a burn unit. Stopping nonessential medications The first and most important step in treating Stevens-Johnson syndrome is to discontinue any medications that may be causing it. So I have this.seems that some people have a rare reaction to the Plaquenil that causes sever inflamationand cell death actaully of the mucus membranes steven-johnson syndrome. Which are in your. View detailed reports from patients taking plaquenil who experienced stevens-johnson syndrome. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil steven johnson syndrome Stevens-Johnson syndrome in association with., Plaquenil and Stevens Johnson Syndrome - Reviews 98 hydroxychloroquinePlaquenil and cyclosporineChloroquine ineffective in exoerythrocyticPlaquenil eczema Stevens-Johnson Syndrome SJS and toxic epidermal necrosis TEN are very serious skin conditions that can happen as a result of illness or as side effects to medications. The skin peeling and blistering means that most people with this condition are hospitalized. Stevens-Johnson Syndrome - Cleveland Clinic. Hydroxychloroquine Sulfate Stevens-johnson Syndrome.. Mother Loses 98 Percent of Skin to Stevens Johnson Syndrome. It is unclear how often Stevens-Johnson syndrome or other rashes occurs with chloroquine use. Although there have been several reported cases of both adults and children developing these rashes while using chloroquine, no studies have looked at how often this actually happens. Stevens-Johnson syndrome SJS and toxic epidermal necrolysis TEN are similar conditions characterized by intraepidermal cell death leading to diffuse vesicobullous eruptions. The differentiating criteria for SJS and TEN is the extent of skin detachment; SJS is defined as 10% total body surface area, SJS-TEN overlap as 10-30%, and TEN as 30%. Stevens-Johnson syndrome SJS is a rare and serious condition of your skin and mucus membranes. SJS will cause you to lose up to 10% of your outer layer of skin. SJS is usually caused by a response to a medicine you have been taking.