While the exact percentage of RA patients who experience sleep problems is hard to nail down, more than 80% of people with RA report fatigue as part of their symptoms. Why Sleep Matters Sleep problems can increase levels of stress hormones and aggravate flares, says Rochelle Rosian, MD, a Cleveland Clinic rheumatologist. Hydroxychloroquine blood tests Hydroxychloroquine does it make you feel dizzy Hydroxychloroquine sulfate answer 3 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil isn't known for causing insomnia. It is also a drug that stays in your system for a long time and takes a long time getting IN to your system. It takes 3-5 months to work and just as long to get out of your system. When you started the Plaquenil, how long did it take until you started having insomnia? Sleeping can be deceptive. WebMD provides information about which foods to avoid while taking Plaquenil Oral. “When you sleep, you make all those brain chemicals that you need to feel better. And even if you’re not flaring, you may not manage your pain as well if you’re not sleeping. Plaquenil and insomnia Plaquenil Uses, Dosage & Side Effects -, Insomnia because of plaquenil DailyStrength Ana and plaquenil Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Lupus is a difficult diagnosis to handle and can really make it difficult to fall asleep. Started taking Plaquenil for Lupus and now I can't sleep.. Foods to Avoid When Taking Plaquenil Oral. Plaquenil. Jan 18, 2009 Plaquenil doesn't usually cause insomnia. It is most likely something else, such as prednisone if you're taking it or anxiety. Insomnia is a common complaint for people with Lupus, some as a result of the steroids and some from general stress of the disease. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil?