It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Massive hydroxychloroquine overdose Chloroquine phosphate and pregnancy What is Hydroxychloroquine, and What Does It Do? According to the American College of Rheumatology, hydroxychloroquine Plaquenil, is a “disease-modifying anti-rheumatic drug DMARD,” meaning that it helps reduce the pain and swelling that come with can also reduce the incidence of joint damage, thus lessening the risk of developing a long-term disability from complications. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil Leflunomide Arava Methotrexate Rheumatrex and Trexall Minocycline Minocin Sulfasalazine Azulfidine Methotrexate is the form of rheumatoid arthritis medication that is most commonly used and it is often used interchangeably with the term DMARD. How are DMARDs Administered? For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil dmard DMARDs Arthritis Foundation, Hydroxychloroquine Plaquenil Complications of chloroquinePharmacokinetics chloroquine miceDoes plaquenil cause skin peeling on handsPlaquenil hemangioma dermatologyWhat if hydroxychloroquine doesn t work Some DMARDs were originally used for other medical conditions and were found to work for RA, as well. For instance, Plaquenil is a malaria drug and methotrexate is a chemotherapy medication. Rheumatoid Arthritis Drugs Demystifying DMARDs. RA Medications What are Disease Modifying Antirheumatic.. Plaquenil Uses, Dosage & Side Effects -. If moderate or high disease activity exists after 3 months of combination DMARDs, an option is to add or switch DMARDs and reassess in another 3 months. For patients with low disease activity without poor prognostic features who have moderate or high disease activity after 3 months of DMARD monotherapy, the addition of methotrexate is an option. Plaquenil hydroxychloroquine "Hi, I was taking the generic form of plaquenil for over 10 years for rheumatoid arthritis. It took a few weeks to see it work but what a change for the better. Less painful joints and fatigue. Always have gotten retina checked and have been good. Then I started getting debilitating migraines. Jun 09, 2006 Other DMARDs. There is no published clinical data addressing the perioperative morbidity of RA patients treated with other commonly used antirheumatic drugs, including hydroxychloroquine Plaquenil™, leflunomide Arava™, azathiaprine Imuran™, or sulfasalazine Azulfidine™.