Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil dosing in renal failure Nortriptyline and plaquenil Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. The drug may be used to treat a type of blood disease called porphyria cutanea tarda. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil medication type Plaquenil Side Effects Common, Severe, Long Term -, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Taking hydroxychloroquine for years now burning skinPlaquenil skin discoloration It belongs to a class of medications known as disease-modifying antirheumatic drugs DMARDs. It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. Hydroxychloroquine 200 mg Tablets Generic Plaquenil. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Side Effects on Your Eyes and Vision. Plaquenil is an anti-malarial drug and contains hydroxychloroquine sulfate. It is used for treatment of malaria, auto-immune diseases like lupus and arthritis. The exact mechanism of action of Plaquenil is not known. Its action against the malarial parasites is similar to the compound chlorquine phosphate. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Prevents and treats malaria, and also treats a type of bowel infection. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria.