Mitochondrial diseases that cause prominent muscular problems are called mitochondrial myopathies (myomeans muscle and pathos means disease), while mitochondrial diseases that causes both prominent muscular and neurological problems are called mitochondrial encephalomyopathies (encephalo refers to the brain). A typical human cell relies on hundreds of mitochondria to meet its energy needs. Hydroxychloroquine 4 cream Dose of chloroquine phosphate Does plaquenil cause hair loss What Is Plaquenil? Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? A case of fatal hydroxychloroquine overdose HT Fung, KK Lam, OF Wong, B Lau, CW Kam. Another presented with slurred speech, drowsiness, blood glucose of 3.2 mmol/L and blood pressure of 63 mmHg by palpation. She was resuscitated with fluid boluses and dopamine. Four hours later, the blood Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. In most cases, mitochondrial disease is a multisystem disorder affecting more than one type of cell, tissue, or organ. The symptoms of mitochondrial disease vary, because a person can have a unique mixture of healthy and defective mitochondria, with a unique distribution in the body. Hydroxychloroquine and slurred speech Slurred speech, unusual movements - Sticky Blood-Hugh., A case of fatal hydroxychloroquine overdose Do chloroquine cause splenomegalyPlaquenil enlarged spleenHydroxychloroquine toxicity eye Mitochondrial myopathies also can cause weakness and wasting in other muscles of the face and neck, which can lead to difficulty with swallowing and, more rarely, slurred speech. People with mitochondrial myopathies also may experience muscle weakness in their arms and legs. Mitochondrial Myopathy Fact Sheet National Institute of.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. What Causes Slurred Speech in Elderly Dysarthria and How is.. I have lupus, sjogren's and antiphospholipid syndrome and have had only mild symptoms, aside from a few flares, since staring plaquenil 5 years ago. Lately, especially when tired at the end of the day, my speech is slurred and I am doing all I can to convince my family I'm not drinking on my way home from work! Has anyone else experienced this. Jun 21, 2018 The person affected by slurred speech generally mumbles and is unable to talk clearly. There is weakness and loss of control over the muscles used for speech. Slurred speech may be associated with other underlying disorders, based on which it may be permanent or temporary. Slurred speech, or dysarthria, usually involves an inability to make a particular motion with the mouth and tongue. Dysarthria causes words that necessitate that movement to sound incomplete or slurred. These are called articulation errors. Slurred speech may sound different depending on the language or the individual affected.