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    Prednisolone is indicated in the management of all conditions deemed likely to benefit from short or long term glucocorticoid therapy. These include: Allergic states Severe, incapacitating allergies unresponsive to conventional treatment; asthma serum sickness; drug hypersensitivity reactions. Collagen disorders Eg systemic lupus erythematosus, polymyositis, polymyalgia rheumatica and temporal (giant cell) arteritis, mixed connective tissue disease syndrome, acute rheumatic carditis. Rheumatic disorders Usually given as an adjunctive therapy for short term administration during an acute episode or exacerbation of rheumatoid arthritis, psoriatic arthritis. Skin conditions Life-threatening or incapacitating skin conditions such as pemphigus and exfoliative dermatitis. Neoplastic disease Leukaemias and lymphomas in adults, acute leukaemia of childhood. Gastro-Intestinal disease During acute exacerbation in ulcerative colitis and regional ileitis (Crohn's Disease). Prednisolone resembles the hormone cortisol made by your adrenal glands. This steroid medication reduces inflammation and is used to treat many conditions, such as allergies, asthma and certain types of arthritis. Prednisolone 5 mg is a low-dose steroid, but side effects can still happen. Long-term effects typically do not develop unless you've been taking prednisolone for several months. You may experience stomach upset within a few days of starting prednisolone, with symptoms such as heartburn, indigestion and nausea. Taking prednisolone with food may help reduce these side effects. You may experience an increased appetite and gain weight if you're eating more than usual. Other possible short-term side effects include restlessness, moodiness, difficulty sleeping, acne breakouts and increased sweating.

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