Lasix vs furosemide

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  1. matimatik New Member

    Lasix vs furosemide


    Edema associated with congestive heart failure (CHF), liver cirrhosis, and renal disease, including nephrotic syndrome 20-80 mg PO once daily; may be increased by 20-40 mg q6-8hr; not to exceed 600 mg/day Alternative: 20-40 mg IV/IM once; may be increased by 20 mg q2hr; individual dose not to exceed 200 mg/dose Refractory CHF may necessitate larger doses Excessive diuresis may cause dehydration and electrolyte loss in elderly; lower initial dosages and more gradual adjustments are recommended (eg, 10 mg/day PO)Increase in blood urea nitrogen (BUN) and loss of sodium may cause confusion in elderly; monitor renal function and electrolytes Anaphylaxis Anemia Anorexia Diarrhea Dizziness Glucose intolerance Glycosuria Headache Hearing impairment Hyperuricemia Hypocalcemia Hypokalemia Hypomagnesemia Hypotension Increased patent ductus arteriosus during neonatal period Muscle cramps Nausea Photosensitivity Rash Restlessness Tinnitus Urinary frequency Urticaria Vertigo Weakness Toxic epidermal necrolysis, Stevens-Johnson Syndrome, erythema multiforme, drug rash with eosinophila and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, bullous pemphigoid purpura, pruritus Agent is potent diuretic that, if given in excessive amounts, may lead to profound diuresis with water and electrolyte depletion Careful medical supervision is required; dosing must be adjusted to patient's needs Use caution in systemic lupus erythematosus, liver disease, renal impairment Concomitant ethacrynic acid therapy (increases risk of ototoxicity) Risks of fluid or electrolyte imbalance (including causing hyperglycemia, hyperuricemia, gout), hypotension, metabolic alkalosis, severe hyponatremia, severe hypokalemia, hepatic coma and precoma, hypovolemia (with or without hypotension) Do not commence therapy in hepatic coma and in electrolyte depletion until improvement is noted IV route twice as potent as PO Food delays absorption but not diuretic response May exacerbate lupus Possibility of skin sensitivity to sunlight Prolonged use in premature neonates may cause nephrocalcinosis Efficacy is diminished and risk of ototoxicity increased in patients with hypoproteinemia (associated with nephrotic syndrome); ototoxicity is associated with rapid injection, severe renal impairment, use of higher than recommended doses, concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs To prevent oliguria, reversible increases in BUN and creatinine, and azotemia, monitor fluid status and renal function; discontinue therapy if azotemia and oliguria occur during treatment of severe progressive renal disease FDA-approved product labeling for many medications have included a broad contraindication in patients with a prior allregic reaction to sulfonamides; however, recent studies have suggested that crossreactivity between antibiotic sulfonamides and nonantibiotic sulfonamides is unlikely to occur In cirrhosis, electrolyte and acid/base imbalances may lead to hepatic encephalopathy; prior to initiation of therapy, correct electrolyte and acid/base imbalances, when hepatic coma is present High doses ( 80 mg) of furosemide may inhibit binding of thyroid hormones to carrier proteins and result in transient increase in free thyroid hormones, followed by overall decrease in total thyroid hormone levels In patients at high risk for radiocontrast nephropathy furosemide can lead to higher incidence of deterioration in renal function after receiving radiocontrast compared to high-risk patients who received only intravenous hydration prior to receiving radiocontrast Observe patients regularly for possible occurrence of blood dyscrasias, liver or kidney damage, or other idiosyncratic reactions Cases of tinnitus and reversible or irreversible hearing impairment and deafness reported Hearing loss in neonates has been associated with use of furosemide injection; in premature neonates with respiratory distress syndrome, diuretic treatment with furosemide in the first few weeks of life may increase risk of persistent patent ductus arteriosus (PDA), possibly through a prostaglandin-E-mediated process Excessive diuresis may cause dehydration and blood volume reduction with circulatory collapse and possibly vascular thrombosis and embolism, particularly in elderly patients Increases in blood glucose and alterations in glucose tolerance tests (with abnormalities of fasting and 2 hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus reported Patients with severe symptoms of urinary retention (because of bladder emptying disorders, prostatic hyperplasia, urethral narrowing), the administration of furosemide can cause acute urinary retention related to increased production and retention of urine; these patients require careful monitoring, especially during initial stages of treatment Hypokalemia may develop with furosemide, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids, ACTH, licorice in large amounts, or prolonged use of laxatives Pregnancy category: C; treatment during pregnancy necessitates monitoring of fetal growth because of risk for higher fetal birth weights Lactation: Drug excreted into breast milk; use with caution; may inhibit lactation Loop diuretic; inhibits reabsorption of sodium and chloride ions at proximal and distal renal tubules and loop of Henle; by interfering with chloride-binding cotransport system, causes increases in water, calcium, magnesium, sodium, and chloride Solution: Fructose10W, invert sugar 10% in multiple electrolyte #2 Additive: Amiodarone (at high concentrations of both drugs), buprenorphine, chlorpromazine, diazepam, dobutamine, eptifibatide, erythromycin lactobionate, gentamicin(? ), isoproterenol, meperidine, metoclopramide, netilmicin, papaveretum, prochlorperazine, promethazine Syringe: Caffeine, doxapram, doxorubicin, eptifibatide, metoclopramide, milrinone, droperidol, vinblastine, vincristine Y-site: Alatrofloxacin, amiodarone (incompatible at furosemide 10 mg/m L; possibly compatible at 1 mg/m L), chlorpromazine, ciprofloxacin, cisatracurium (incompatible at cisatracurium 2 mg/m L; possibly compatible at 0.1 mg/m L), clarithromycin, diltiazem, diphenhydramine, dobutamine, dopamine, doxorubicin (incompatible at furosemide 10 mg/m L and doxorubicin 2 mg/m L; possibly compatible at furosemide 3 mg/m L and doxorubicin 0.2 mg/m L), droperidol, eptifibatide, esmolol, famotidine(? ), fenoldopam, gatifloxacin, gemcitabine, gentamicin(? ), hydralazine, idarubicin, labetalol, levofloxacin, meperidine, metoclopramide, midazolam, milrinone, morphine, netilmicin, nicardipine, ondansetron, quinidine, thiopental, vecuronium, vinblastine, vincristine, vinorelbine Not specified: Tetracycline Additive: Cimetidine, epinephrine, heparin, nitroglycerin, potassium chloride, verapamil Syringe: Heparin Y-site: Epinephrine, fentanyl, heparin, norepinephrine, nitroglycerin, potassium chloride, verapamil(? ), vitamins B and C Injection: Inject directly or into tubing of actively running IV over 1-2 minutes Administer undiluted IV injections at rate of 20-40 mg/min; not to exceed 4 mg/min for short-term intermittent infusion; in children, give 0.5 mg/kg/min, titrated to effect Use infusion solution within 24 hours The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. Furosemid ist ein Arzneistoff aus der Gruppe der Schleifendiuretika. Schleifendiuretika führen zur Ausscheidung großer Mengen von Gewebeflüssigkeit, indem sie in der Niere im aufsteigenden Teil der Henle-Schleife ein Transportprotein (den Na-K-2Cl Cotransporter) hemmen. Bei intravenöser Gabe des Medikaments sind Ausscheidungsmengen von bis zu 50 Liter pro Tag möglich. Es handelt sich um ein stark harntreibendes Mittel. Bei oraler Einnahme wird Furosemid im biopharmazeutischen Klassifizierungssystem auf Grund seiner schlechten Löslichkeit und schlechten Permeabilität in die Klasse IV eingeteilt. Die schlechte Löslichkeit beruht vor allem auf der Säurestruktur, welche eine sehr schlechte Löslichkeit bei niedrigen p H-Werten bedingt. Bei neutralem p H-Wert ist Furosemid einigermaßen gut löslich. Die schlechte Permeabilität wird zum Teil durch die Affinität zu einer intestinalen Effluxpumpe bedingt, die aber bislang noch nicht genau beschrieben ist.

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    Furosemide versus Torsemide - comparative analysis covers differences between Furosemide and Torsemide, and similar featuresFurosemide. Torsemide. Brand names. Lasix®. Demadex®. Torasemid TOREM, UNAT wird mit den Argumenten beworben, dass es a weniger "Sturzdiurese" auslöse als Furosemid LASIX u.a. und daher von den. Medscape - Hypertension-specific dosing for Lasix furosemide, frequency- based. contraindications, pregnancy & lactation schedules, and cost information.

    Furosemide significantly increases urination which relieves excess fluid, but its use may also lead to the depletion of certain electrolytes in the body (such as potassium). Prescribed for Edema, Heart Failure, High Blood Pressure, Ascites, Hypercalcemia, Nonobstructive Oliguria, Oliguria, Pulmonary Edema, Renal Failure, Renal Transplant. furosemide may also be used for purposes not listed in this medication guide. " Furosemide significantly increases urination which relieves excess fluid, but its use may also lead to the depletion of certain electrolytes in the body (such as potassium). more Lasix is a strong diuretic that increases urination which relieves excess fluid from the body. This may also lead to the depletion of certain electrolytes, such as potassium. Prescribed for Edema, Heart Failure, High Blood Pressure, Ascites, Hypercalcemia, Nonobstructive Oliguria, Oliguria, Pulmonary Edema, Renal Failure, Renal Transplant. Lasix may also be used for purposes not listed in this medication guide. Bei Aszites sollte bevorzugt der Aldosteronantagonist Spironolacton eingesetzt werden. Furosemid wirkt überwiegend im aufsteigenden Schenkel der Henle-Schleife und hat ebenfalls eine geringe Aktivität im proximalen Tubulus. Die Substanz ist bei Alkalose, Azidose und verminderter glomerulärer Filtration wirksam. Der genaue Wirkungsmechanismus von Furosemid ist noch nicht vollständig geklärt. Furosemid wirkt wahrscheinlich am Natrium-Kalium-2Chlorid-Cotransportsystem (Na-K-2Cl-Cotransporter) und hemmt hier kompetitiv den Chloridtransport und indirekt die Natrium- und Kaliumreabsorption. Gabe sofort eintritt, basiert vermutlich auch auf einer Steigerung der Nierendurchblutung. Für chronische Zustände wird Furosemid oral verabreicht. Für Notfälle wie Lungenödeme appliziert man Furosemid wegen der schnellen Wirkung intravenös.

    Lasix vs furosemide

    Furosemide, Lasix Drug Facts, Side Effects and Dosing - MedicineNet, TORASEMID TOREM, UNAT BESSER ALS FUROSEMID LASIX.

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  4. Compare Furosemide vs Lasix head-to-head for uses, ratings, cost, side effects, interactions and more. Furosemide rated 7.3/10 vs Lasix rated 7.3/10 in overall.

    • Furosemide vs Lasix Comparison -.
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    At A Tale of Two Chefs, our goal is to exceed our client's expectations and to remind them of the simple beauty in great tasting food. We provide Specialty Catering and Private Chef Services in Chicago or wherever our clients need us. Pictures of Lasix Furosemide, drug imprint information, side effects for the patient. Atrial FibrillationVisual Guidelines to Causes, Tests and Treatment. Noun. - A diuretic used in the treatment of congestive heart failure and edema. Best known under the trade name Lasix.

     
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