I do have anxiety disorder but have not had a panic attack in two years and certainly not waves of panic. I have since lost my appetite and can only eat a little. Eye 5est to check eyes when taking plaquenil Sd oct plaquenil Plaquenil side effects mayo clinic I was on Plaquenil for a few days and I had severe anxiety attacks, couldn't breathe, I stop taking it and was better. I told my reumatologist and he kind of scoffed at me and told me to try again. I did and same thing happened. Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I’ve taken Plaquenil before with no ill effects but quit taking it as I just got too lazy to remember. Well, i’m Back on it and like after a week of taking it, my anxiety has gotten so bad that my appetite has gone way down and I feel nervous all the time and have negative thoughts like my life is meaningless. This didn't make me happy because I really feel that looking for more medication from someone else for sudden symptoms is not a wise choice. It helped me sleep but makes me way too tired during the day -- so it is like I am anxious, panicky, and exhausted now. She said right away that she does not think it is the plaquenil and then suggested I see a psychiatrist. Plaquenil anxiety depression Anxiety and Plaquenil Has anyone experienced mood. - LUPUS UK, Plaquenil Side Effects Common, Severe, Long Term - Plaquenil low dose I have to agree. My pre-existing, and medicated anxiety, depression and panic is at an all time high. The only new factor is CellCept which I've been on for 5 months now at 3000mg daily. I also take Plaquenil and prednisone 5-7.5mg I have not been able to get off prednisone for the 3 yrs since my diagnosis-I flare as soon as I try to wean down. Cellcept and anxiety/depression DailyStrength. Has anyone experienced anxiety after/ while taking Plaquenil?. How long does it take for plaquenil to leave your system?. Plaquenil and anxiety/depression? - Autoimmune diseases. and my joints were sore so I went back up to my original dose of 400mg but immediately experienced severe and sudden anxiety and depression. I am also on 150mg of zoloft for GAD, OCD and depression which I have largely had under control for the past ten years with occasional little. Does Plaquenil affect your temperament. To cut a long story short, my new specialist has put me on plaquenil. For the best part I can notice no change in anything apart from being SO arguementative, being verbally very aggressive and feeling totally out of control. It is causing huge problems btwn my partner and I as he seems to be the. I have had chronic, clinical depression my entire life which I am on meds for. The Plaquenil GREATLY effected by depression. I am no longer taking it. If you Google 'Plaquenil Depression' you will see that it has this effects on others. That's how I got to this post! Hopefully there is something else I can try to deal with my symptoms.