Metformin (brand names Glucophage, Glucophage XR, Fortamet, Riomet, Glumetza, and others) is a popular and highly effective oral diabetes drug used to help manage Type 2 diabetes. This drug works by lowering the amount of glucose made by the liver and by making the body’s cells more sensitive to insulin. Metformin also has some other beneficial effects in that it may help lower blood lipid, or fat, levels (cholesterol and triglycerides) and can, in some people, promote a small amount of weight loss. Metformin can be used with other diabetes pills and with insulin. Side effects of taking metformin are relatively rare, the most common being bloating, nausea, and diarrhea, all of which are temporary. Some people shouldn’t take metformin, including people with kidney disease, liver disease, or congestive heart failure, for example, because of an increased risk of a potentially fatal condition called lactic acidosis. 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Metformin helps to lower your blood glucose to as normal a level as possible. • If you have any further questions, ask your doctor or pharmacist. • If any of the side effects become troublesome, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. This leads to a high level of glucose in your blood. It may harm them, even if their symptoms are the same as yours. If you have diabetes, your pancreas does not make enough insulin or your body is not able to use properly the insulin it produces. Your body uses glucose to produce energy or stores it for future use. Insulin is a hormone produced by the pancreas that makes your body take in glucose (sugar) from the blood. It belongs to a group of medicines called biguanides. Further information 1 WHAT METFORMIN IS AND WHAT IT IS USED FOR What Metformin is Metformin contains metformin, a medicine to treat diabetes. Metformin is an oral diabetes medicine that helps control blood sugar levels. 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