According to legend it was first brought to Europe by a Countess who had been treated with it in Peru in the 1600s. In 1820, two French chemists isolated quinine from the cinchona bark and quinine became a treatment of reference for intermittent fever throughout the world. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. Keflex and plaquenil Coding eye exam for plaquenil Buy aralen medication Usual Adult Dose for Malaria. 60 kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days Total dose 2.5 g chloroquine phosphate 1.5 g base in. Chloroquine has been the drug of choice for protecting against malaria. But because of resistance, it is now only suggested for use in areas where Plasmodium vivax, P oval, and P malariae are present. Chloroquine is the drug of choice for treating most patients with malaria caused by P. vivax, P. ovale, P. malariae and chloroquine-sensitive strains of P. falciparum. However, due to the development of resistance, chloroquine is ineffective against most strains of P. falciparum in South America, Africa and Asia. These compounds belonged to a new class of antimalarials, the four-amino quinolines. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin (chloroquine) and Sontochin (3-methyl-chloroquine). Chloroquine resistant malaria drug of choice Chloroquine-Resistant Malaria –, Malaria MedlinePlus Medical Encyclopedia Chloroquine phosphate and leather coralThe mainstay of treatment for malaria is chloroquineRetinal pigment epithelial mottling of macula plaquenilHow does plaquenil treat ra For destinations where any chloroquine-resistant malaria is present, in addition to mosquito avoidance measures, prophylaxis options are atovaquone-proguanil, doxycycline, mefloquine, and tafenoquine. Malaria - Chapter 4 - 2020 Yellow Book Travelers' Health CDC. Treatment_of_malaria TUSOM Pharmwiki. CDC - Malaria - Diagnosis & Treatment United States.. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug. Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link Chloroquine is the drug of choice for the prophylaxis and treatment of sensitive malaria species during pregnancy. Chloroquine should only be given during pregnancy when need has been clearly established. See references. Chloroquine Breastfeeding Warnings. Chloroquine is excreted into human milk. Treatment of P. vivax infections. P. vivax infections should be treated with an ACT or chloroquine in areas without chloroquine-resistant P. vivax. In areas where chloroquine-resistant P. vivax has been identified, infections should be treated with an ACT, preferably one in which the partner medicine has a long half-life.