In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Nigeria malaria chloroquine resistance Interaction between plaquenil and augmentin ibuprofen Visual fields in chloroquine Sensorineural hearing loss and plaquenil How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. I completely agree with Lynnwood that plaquenil helps stop the progression of your disease, so the longer you wait the worse your Sjogren's becomes. Plaquenil is a fairly benign medication and was originally developed to protect against malaria. Later it was found to help autoimmune diseases. It can be months before you get relief with plaquenil. My rheumy has just prescribed Plaquenil for my SS. Reading the warnings, I see that there is concern about effects on the eyes retinas. I am very concerned about this and am wondering if anyone out there has been put on an alternative drug to treat their SS. I have several issues with my. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Alternatives to plaquenil for sjogrens Plaquenil Compared to Alternatives -, Treatment/Plaquenil - Stopping plaquenil headachesHydroxychloroquine and ibuprofenPlaquenil and acetaminophen It seems to help me similar to plaquenil. The funny thing is, that at one point I was on low doses of both at the same time and they didn’t help. I switched doctors and he put me on a higher dose of only plaquenil and I improved immediately. When I stopped plaquenil I went without anything for a few months and started to go down hill. Alternative to Planquenil Sjogrens. Alternatives to Plaquenil DailyStrength. AutoimmuneGal My Story of Cranial Neuropathies and Sjogren’s. Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. In Sjögren’s, Plaquenil is used to treat many symptoms. While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results some show benefit and some show no benefit. For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system.