Please review the following URL and make sure that it is spelled correctly. Requested URL: /Portals/0/Files/Hydroxychloroquine... Plaquenil and mctd Effects of plaquenil on the eyes Chloroquine ferroquine and ruthenoquine structure Glucose-6-phosphate dehydrogenase G6PD deficiency is associated with hemolysis and renal impairment; use with caution. Dermatologic reactions to hydroxychloroquine may occur. Patients are prone to dermatitis outbreaks Rarely, hydroxychloroquine can lead to anemia in some individuals. This can happen in individuals with a condition known as G6PD deficiency or porphyria. In rare cases, hydroxychloroquine can cause visual changes or loss of vision. Such vision problems are more likely to occur in individuals taking high doses for many Two G6PD-deficient patients experienced hemolysis during severe lupus flares that occurred while not taking HCQ. “This is the largest study to date evaluating G6PD deficiency with concurrent use of HCQ,” the researchers concluded. Regardless of the problem, we'd like to help you find what you're looking for. The page you are trying to reach is not available on our site. The page name may have changed, you may have happened upon a broken link, or the URL may be entered incorrectly. G6pd hydroxychloroquine UpToDate, PATIENT FACT SHEET Hydroxychloroquine Plaquenil Treatment for eye issues after taking plaquenilMelton and thomas plaquenilChloroquine warnings There is no data to support the withholding of hydroxychloroquine HCQ therapy among African American patients with glucose-6-phosphate dehydrogenase G6PD, according to the results of a recent review. Is Hydroxychloroquine Safe for Patients with G6PD Deficiency? IAN. Is Hydroxychloroquine Safe for Patients with G6PD Deficiency.. Hydroxychloroquine DermNet NZ. If mutations in the G6PD gene reduce the amount of glucose-6-phosphate dehydrogenase or alter its structure, this enzyme can no longer play its protective role. As a result, reactive oxygen species can accumulate and damage red blood cells. Background/Purpose Hydroxychloroquine HCQ is frequently used to treat autoimmune diseases. The HCQ package insert and online drug information resources report an increased risk of hemolytic anemia in patients with G6PD deficiency. However, no published studies quantify this potential risk, and the genetic forms of severe G6PD enzyme deficiency are very rare in the United States. Rarely, hydroxychloroquine can lead to anemia in some individuals. This can happen in individuals with a condition known as G6PD deficiency or porphyria. In rare cases, hydroxychloroquine can cause visual changes or loss of vision.