Inflammatory arthritis affects the immune system which controls how well your body fights off infections. Also, many medications given to treat inflammatory arthritis can weaken the immune system. Chloroquine for treating malaria Side effects of too much plaquenil Plaquenil weight gain lupus Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. I have a 21 yr. old lupus nephritis patient on mycophenolate, hydroxychloroquine and prednisone 40 mg per day. She says both her current nephrologist and her prior pediatric rheumatologist told her NOT to get pneumococcal and flu vaccines. Pneumococcal vaccine killed, commonly called the “pneumonia vaccine” influenza vaccine killed, commonly called the “flu shot” or “flu vaccine” Both of these vaccines are strongly recommended for people with inflammatory rheumatic diseases like lupus. Rheumatoid arthritis and lupus are the most common types of inflammatory arthritis. People with weakened immune systems are at high risk for getting more severe illness and complications such as hospitalization with the flu. Flu shot and hydroxychloroquine Hydroxychloroquine Oral Uses, Side Effects, Interactions., Should Lupus Patients Receive Influenza and Pneumococcal Vaccines. Chloroquine marine ichChloroquine natural source I have RA and am presently being treated with Prednisone5mgand Plaquenil. Wondering if it is ok to take Hep A and B vaccines while on these meds. Answer. Yes. Both vaccines are safe with your current medications. The flu shot and pneumonia vaccine are also safe. Vaccines while Taking Prednisone and Plaquenil - Arthritis Information. What Every Person With Lupus Should Know About Vaccines. Flu shot question -. Unless your doctor recommends otherwise, you should get the flu shot every year. “Vaccines decrease patients’ susceptibility to specific infections, so all high-risk patients, particularly those who are elderly and/or those on immunosuppressive agents, should receive the flu vaccine unless there is a contraindication,” Dr. Wu says. User Reviews for Hydroxychloroquine to treat Undifferentiated Connective Tissue Disease. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.