Nigeria malaria chloroquine resistance

Discussion in 'Canada Drugs' started by DreamWalkerTg, 28-Feb-2020.

  1. [email protected] New Member

    Nigeria malaria chloroquine resistance


    Resistance to currently available antimalarial drugs has been confirmed in only two of the four human malaria parasite species, first developed independently in three to four areas in Southeast Asia, Oceania, and South America in the late 1950s and early 1960s. Since then, chloroquine resistance has spread to nearly all areas of the world where falciparum malaria is transmitted.

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    The term “chloroquine resistance” can lead to misunderstandings when it is considered by some to refer to in vitro phenotypes, by others to refer to the ability of malaria parasites to survive chloroquine at therapeutic serum concentrations in vivo, and yet by others to refer to the outcome of a clinical episode after chloroquine therapy. The drug proved very strong for a long time in preventing malaria before the malaria parasite developed resistance to it. Naija News understands that chloroquine has been used in clinical trials in more than 10 hospitals in China’s capital, Beijing, and Sun said that the clinical evidence from over 10 hospitals in Beijing provinces and “has shown fairly good efficacy”. Resistance to anti- malarial drugs in patients is becoming a worrisome phenomenon in Nigeria. It has posed serious challenge of combating malaria in most parts of the world.

    Although resistance to these drugs tends to be much less widespread geographically, in some areas of the world, the impact of multi-drug resistant malaria can be extensive. Has also developed resistance to nearly all of the other currently available antimalarial drugs, such as sulfadoxine/pyrimethamine, mefloquine, halofantrine, and quinine.

    Nigeria malaria chloroquine resistance

    Chloroquine not cure for coronavirus –NMA – Punch Newspapers, New Discovery Reveals Africa's Anti-Malaria Drug.

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  3. The development of chloroquine resistance by malaria parasites is increasing at an alarming rate especially in the tropical countries where it is used extensively as an antimalarial drug 2. In the past years, the drug of choice has changed from chloroquine to artemisinin.

    • Chloroquine Resistance in Plasmodium falciparum - microbewiki.
    • Nigeria Why New Malaria Strain Resists Drugs -.
    • Nigeria Chloroquine Making a Comeback Against Malaria..

    The agency's director-general, Mojisola Adeyeye, urged Nigerians to desist from using chloroquine as an anti-malaria drug because of the resistance that has been proven to develop in the past. Facts about malaria in Nigeria. In Nigeria, malaria is endemic. Accounts for 60% of outpatient visits. Responsible for 30% of under-5 mortality. Resurgence of malaria is observed in recent times. Resurgence due to increasing resistance to chloroquine & sulfadoxine-pyrimethamine. Apr 01, 2017 Chloroquine was banned as a first line treatment drug for malaria in Nigeria in 2005. The decision, based on the recommendation of the World Health Organisation, was taken by the Federal Ministry.

     
  4. jingle New Member

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  5. Does Patient with Lupus Have Plaquenil Retinopathy? The patient reported being diagnosed with systemic lupus erythematosus SLE two years prior and secondary kidney and liver dysfunction. She said she was treated with 200mg to 400mg of Plaquenil hydroxychloroquine sulfate, Sanofi-Synthelabo per day for her lupus 4.4mg/kg to 8.8 mg/kg per day for two years with a cumulative dose of 276g. The patient said she was also prescribed prednisone for her lupus; the dose had been tapered from 5mg/day to 1mg/day.

    Protecting your eyesight when taking Plaquenil Lupus.