But Chloroquine has significantly higher rate of retinal toxicity, so it isn't used much anymore. Also, Plaquenil appears to effectively reduce flares in patients with lupus not necessarily by suppressing immunity. Read more Anxiety over potential eye problems with Hydroxychloroquine is completely unwarranted if the dose is kept below 6mg/kg (2.2lbs) of body weight. Read more See 1 more doctor answer It can cause eye problems so you need to see an ophthalmologist and peridoic screenings. Read more Results are very good, particulary when used alone and better with methotrexate. Bob & aralene goldberg foundation Dosing of aralen How does Plaquenil work? Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. How do you take Plaquenil? You take Plaquenil as a pill 1 or 2 times a day. Take the pills with food or milk. I originally took Plaquenil Sanofi but this brand is now discontinued. The generic form of this, on my prescription, gives me serious digestion and stomach upsets to a point I spent months trying to figure out what I thought was irritable bowel syndrome. Has anyone found a good alternative UK brand that doesn't create this side affect. Plaquenil is sold in 200mg tablets. The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended. Chloroquine can be substituted for Plaquenil but only in limited circumstances. Please provide more detailed information if you want a more specific answer. Read more See 1 more doctor answer Depends on what you are being treated for.... Read more While plaquenyl is a slow acting but effective drug, Prednisone is used in much higher doses in active sle. Arthritis (non-deforming) or arthralgias associated with the disease will have substantial pain relief with a dose this low. It's infusion intervals are longer, because the turnover of recptors is slower than the production of tnf-a itself. So other meds like Imuran and Cell Cept (mycophenolate mofetil) also reduce flares, but also increases infection. Read more It depends why you are taking Plaquenil in the first place. Apart from some stomach quiziies, I have never stopped this drug, as long as it demonstrated it is working. Other than that we see a few people who have increased skin pigmentation called "plaquenil ochronosis". The dirrence with Remicade (infliximab) is that it blocks the tnf-a receptor, rather than binding tnf-a itself, but it accomplishes the same thing. Lupus alternatives to plaquenil Lupus Medications and Treatments, Hydroxychloroquine - Plaquenil Alternative - LUPUS UK Plaquenil eye screening guidelinesQuit plaquenilLeflunomide and plaquenil taken togetherHydroxychloroquine pt teachingChloroquine bioavailability Hydroxychloroquine, brand name Plaquenil, is a time-tested and often-used medication that is typically a first line of defense in the treatment of autoimmune conditions such as RA and lupus. Plaquenil Shortage Leaves RA, Lupus Patients in Pain and.. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. I am so afraid to take plaquenil for lupus treatment! any natural cure? Does anyone has an experience with plaquenil? or some one knows a natural way to cure lupus? I am currently taking oil fish, cellfood and recovery for joint pain and multi-vitamins. Has anyone not been able to tolerate plaquenil hydroxychloroquine and/or chloroquine - what have been your alternatives. which is the complete opposite of my normal personality. Luckily my normal Lupus symptoms are not very advanced yet so the DR. has me on 200mg 1x daily and after about 2.5months I seem to be handling that just fine. Plaquenil is used to treat fatigue, pain, skin rashes, and inflammation, especially around the lungs. It is one of the most frequently used medications for lupus because studies show that it may prevent lupus flares and kidney damage. Many lupus patients will stay on Plaquenil for many years and perhaps indefinitely.