Metformin risks

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  1. Yura78 Well-Known Member

    Metformin risks


    Metformin (also known by generic name Glucophage) is an oral hypoglycemic medication used to control high blood sugar. It is used in managing Type II diabetes, in the cases when the body’s high blood sugar levels cannot be properly controlled through exercise, diet and weight management alone. In some cases, patients use Metformin along with other anti-diabetic drugs like glyburide and insulin. Metformin is the only drug of biguanide type (blood sugar controlling drugs) that has been allowed by US FDA and has been widely used as a to-go medication for Diabetes, as well as some other conditions (such as polycystic ovary syndrome, gestational diabetes, and others). by decreasing blood sugar production, reducing hyperglycemia, reducing triglycerides, improving transport of insulin and helping in weight management. In combination, all those factors lead to much-improved insulin sensitivity, which is especially helpful in cases of insulin resistance. Another way metformin is helpful to diabetic and pre-diabetic patients is that is has been shown to slow down and reduce the absorption of carbohydrates through intestines, which further helps control blood sugar levels. Hemoglobin A1c (Hb A1c) is a test used to measure long-term blood sugar control in people with diabetes. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. Normal Hb A1c levels are usually less than 6 percent in people without diabetes, and people with diabetes usually have higher Hb A1c levels. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy. In one study, people who took metformin reduced their Hb A1c levels by 1.4 percent, compared to a gain of 0.4 percent in people who did not take metformin. Princeton, NJ: Bristol-Myers Squibb Company;2006 June. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your Health Savvy programs. Studies have shown that the higher the Hb A1c, the greater the chance for developing long-term problems related to diabetes. Are you still sure that you want to clear all of you selected topics? This includes problems such as heart disease, diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. By getting blood sugar levels under control with metformin, it may be possible to decrease the chances for developing these diabetes complications. Jacksonville, FL: Ranbaxy Pharmaceuticals, Inc.;2004 May. Site users seeking medical advice about their specific situation should consult with their own physician.

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    Metformin, marketed under the trade name Glucophage among others, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are. While there may be many medical reasons to take metformin beyond just type 2 diabetes, a thorough discussion about the role of metformin therapy, and the risks versus benefits, should take place before a patient starts any medication, including metformin. Metformin helps by reducing the amount of sugar, or glucose that is produced by the liver and also helps release the glucose from the liver into the body.

    Commonly reported side effects of metformin include: lactic acidosis, diarrhea, nausea, nausea and vomiting, vomiting, and flatulence. Other side effects include: asthenia, and decreased vitamin b12 serum concentrate. Riomet (met FORMIN)." Ranbaxy Pharmaceuticals, Jacksonville, FL. See below for a comprehensive list of adverse effects. Glumetza (met FORMIN)." Biovail Pharmaceuticals Canada, Mississauga, IA. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Applies to metformin: oral solution, oral tablet, oral tablet extended release Along with its needed effects, metformin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking metformin: Some side effects of metformin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Metformin ist ein Arzneistoff aus der Gruppe der Biguanide, der in der Regel bei nicht insulinabhängiger Zuckerkrankheit (Diabetes mellitus Typ 2) und insbesondere bei leichtem Übergewicht (Präadipositas) und krankhaftem Übergewicht (Adipositas) eingesetzt wird. Es ist eines der am längsten und das am häufigsten verabreichte orale Antidiabetikum. Das molekulare Wirkprinzip von Biguaniden ist nach wie vor nicht vollständig geklärt. Klinische Studien zeigen, dass Metformin die Glucose-Neubildung in der Leber hemmt. Experimentelle Studien ergaben, dass Metformin die mitochondriale Glycerin-3-phosphat-Dehydrogenase hemmt. In Folge stehen im Zytosol (siehe auch Glycerin-3-phosphat-Shuttle) weniger Metabolite für die Glucose-Neubildung zur Verfügung, und Laktat fällt vermehrt an. Die seltene Nebenwirkung der Laktatazidose bei Überdosierung kann damit erklärt werden.

    Metformin risks

    Benefits of Metformin - Diabetes Home Page, Metformin New Benefits and Risks For This Old

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  3. Metformin official prescribing information for healthcare professionals. Includes indications, dosage, adverse reactions, pharmacology and more.

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    Learn about the potential side effects of metformin. Includes common and rare side effects information for consumers and healthcare professionals. Metformin is used alone or with other medications, including insulin, to treat type 2 diabetes condition in which the body does not use insulin normally and, therefore, cannot control the In patients with type 2 diabetes not at glycemic goal, adding a sulfonylurea to metformin appears to be much safer than switching.

     
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