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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. Tocris products are intended for laboratory research use only, unless stated otherwise. Keywords: Trazodone hydrochloride, Trazodone hydrochloride supplier, 5-HT2A, alpha1, a1, α1, adrenoceptor, antagonist, antagonism, neuronal, differentiation, antidepressant, neuroprotectant, e IF2alpha, e IF2a, e IF2α, inhibitors, inhibits, Receptors, Adrenergic, Alpha-1, Neural, Stem, Cells, PERK, 6336, Tocris Bioscience $50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* or download your copy today! *Please note that Tocris will only send literature to established scientific business / institute addresses. 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Trazodon wird zur Behandlung von Depressionen mit oder ohne begleitende Angststörung, Schlafstörungen und im Rahmen von Depressionen auftretenden erektilen Dysfunktionen ohne schwerwiegende organische Ursachen eingesetzt. -Rezeptoren, deren Aktivierung allgemein mit Schlaflosigkeit, Angst, psychomotorischer Unruhe sowie mit Störungen der Sexualfunktion in Verbindung gebracht wird. Neben Nefazodon zählt es deswegen zu den dualserotonergen Antidepressiva (DSA). Die Serotonin-Wiederaufnahmehemmung ist verhältnismäßig schwach ausgeprägt und kommt dosisabhängig erst in höheren Dosierungen zur Wirkung. Durch die Blockade der 5-HT2a-Rezeptoren wird die über die 5-HT1A-Rezeptoren vermittelte serotonerge Neurotransmission verstärkt. Außerdem hemmt Trazodon stark die α1- und schwach die α2- und H1-Rezeptoren und hat eine abschwächende Wirkung auf den Tremor. 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