Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil 200 mg cost Hydroxychloroquine sulphate tablets uses Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. If you are taking hydroxychloroquine for a long period of time, your doctor will recommend frequent eye exams. It is very important that you keep these appointments. Hydroxychloroquine can cause serious vision problems. If you experience any changes in vision, stop taking hydroxychloroquine and call your doctor immediately. It is possible to detect early signs of hydroxychloroquine retinopathy using specialized techniques that can look at layers of the retina with photographs of the eye, and by visual field testing. Visual field testing is tested by an individual pressing a button when they see a light on a specialized type of eye test. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Hydroxychloroquine test for eyes Hydroxychloroquine retinopathy A review of imaging, Hydroxychloroquine MedlinePlus Drug Information Plaquenil pericardial effusionCan you take hydroxychloroquine and xanax togetherPlaquenil causes nausea Multifocal Electroretinopathy measures electrical responses of various cell types in the retina. It is thought that although the bull’s eye seen on ophthalmic exam represents a disruption of the pigmented part of the retina, it is the photoreceptors that are the targets of hydroxychloroquine toxicity. My Take on New Ocular Screening Guidelines for Plaquenil.. RCOphth guideline Hydroxychloroquine and Chloroquine Retinopathy NEW.. Eye screening for patients taking hydroxychloroquine Plaquenil. Plaquenil is usually used for long term disease control, rather than in the short term to control active bursts of inflammation. Plaquenil has important but uncommon side effects that may affect your eye. How does Plaquenil affect your eyes? Today it is recommended that every single person on Plaquenil get a visual field 10-2 test, plus one of the three other highly sensitive screening tests the FAF fundus autofluorescence imaging, the SD-OCT spectral domain optical coherence, or the multifocal electroretinogram mfERG,” Thomas says. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. The tests they may do include eye exams.