Can tamoxifen cause weight loss

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  1. Wuwei XenForo Moderator

    Can tamoxifen cause weight loss


    Many people gain weight when they are treated with chemotherapy and steroids. Your extra weight may hang around and increase after chemotherapy if you also take hormonal therapy (tamoxifen or an aromatase inhibitor). If your body shifts into menopause because of chemotherapy, there's a tendency to gain weight. This weight gain may be because of the enzyme lipoprotein lipase (LPL), which is controlled by insulin. LPL sits on the surface of cells and pulls fat out of the bloodstream and into the cell. If LPL is on a muscle cell, it pulls fat into the cell where it’s used for fuel. If LPL is on a fat cell, it pulls fat into the cell and makes it fatter. Another reason for weight gain is the use of corticosteroids. Some gain less, while others put on as many as 25 pounds. It’s common for women who have chemotherapy to gain about 5 to 14 pounds over a year. Menopause also causes you to gain more body fat and lose lean muscle. These medications help with nausea and swelling, or to stop reactions to chemotherapy. Corticosteroids are hormones that can also cause an increase in fatty tissue. Women treated with steroids may also put on pounds, but the weight gain is usually seen only after weeks of continuous use. They can make you lose muscle mass in your arms and legs, and gain belly fat, too. Some research suggests that weight gain is also related to lack of exercise . When you get your cancer treatment, it’s common to feel stress and have some fatigue, nausea, or pain.

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    Tamoxifen can reduce the risk of a breast cancer recurrence, but many women complain of side effects like hot flashes and weight gain. Weight loss is found among people who take Tamoxifen citrate, especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take medication Zometa, and have High blood pressure. To make sure you can safely take tamoxifen, tell your doctor if you have any of these conditions. Q Does tamoxifen cause weight gain?

    Tamoxifen is used in breast cancer treatment and to prevent recurrence after treatment. It’s also sometimes used to prevent breast cancer in those at high risk of the disease. It’s been shown to be effective for hormone-receptor-positive breast cancer. The medication belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). These drugs work by attaching to estrogen receptors in breast cells to minimize estrogen’s effects on breast tissue. Tamoxifen is prescribed mostly to women, but some men, too. One concern with tamoxifen is the possibility of weight changes. If so, we’re going to talk about how you can challenge your beliefs and assumptions and beat this extra weight. (Keeping reading, we’ll pick Kathy’s story back up soon.)Is weight gain something you’re struggling with now? But first, let’s start with: Tamoxifen is a medication prescribed for breast cancer treatment. And, as a preventative measure for women at high risk of developing breast cancer. It works by attaching to estrogen receptors and blocking the effects of estrogen on the breast tissue. So it helps prevent the growth of breast tumors that need estrogen; which, according to the National Cancer Institute, is about 80%. The benefits of tamoxifen are tremendous, but it’s not without risk of side effects.

    Can tamoxifen cause weight loss

    Tamoxifen Side Effects in Women - Imaginis, Who have Weight loss with Tamoxifen citrate - from FDA.

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  4. A look at the link between tamoxifen and weight gain. Included is detail on why weight gain can occur in breast cancer treatment, and other side.

    • Does tamoxifen cause weight gain? - Medical News Today.
    • Tamoxifen Nolvadex - Side Effects, Dosage, Interactions - Drugs.
    • Tamoxifen and weight gain again. - Breast Cancer Care Forum..

    Exercise is a vital part of any weight-loss strategy. If the tamoxifen is causing fatigue, which is a common side effect, exercise may combat it. Start off with 10 minutes of exercise three times a day -- this will add up to the recommended 150 minutes of exercise weekly. More importantly, however, is the weight gain observed in women treated for. the opportunity to encourage exercise to combat the side effects of this. The addition of hormone therapy to tamoxifen does not prevent hot. When the side effects of Tamoxifen were explained to me I was told that I would. I can say that MANY women report weight gain but my Oncologist keep saying.

     
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