Clonidine, sold as the brand name Catapres among others, is a medication used to treat high blood pressure, attention deficit hyperactivity disorder, drug withdrawal (alcohol, opioids, or smoking), menopausal flushing, diarrhea, and certain pain conditions. Clonidine is used to treat high blood pressure, attention deficit hyperactivity disorder (ADHD), drug withdrawal (alcohol, opioids, or smoking), menopausal flushing, diarrhea, and certain pain conditions. It can alleviate opioid withdrawal symptoms by reducing the sympathetic nervous system response such as tachycardia and hypertension, as well as reducing sweating, hot and cold flashes, and general restlessness. Clonidine also has several off-label uses, and has been prescribed to treat psychiatric disorders including stress, sleep disorders, and hyperarousal caused by post-traumatic stress disorder, borderline personality disorder, and other anxiety disorders. Clonidine has also been used to treat refractory diarrhea associated with irritable bowel syndrome, fecal incontinence, diabetes, withdrawal-associated diarrhea, intestinal failure, neuroendocrine tumors and cholera. The reduction in circulating norepinephrine by clonidine was used in the past as an investigatory test for phaeochromocytoma, which is a catecholamine-synthesizing tumour, usually found in the adrenal medulla. In a clonidine suppression test plasma catecholamine levels are measured before and 3 hours after a 0.3 mg oral test dose has been given to the patient. Clonidine high, or its other names: Clonidine, Clophelin, Katalpressan, Hemiton, Attensin, Capresin, Clonidone, Hyposin, Kapvay is an antihypertensive agent that acts at the level of neurohumoral regulation of vascular tone and is used to treat hypertension, glaucoma, and migraine. In this article you can find out Clonidine side effects, what precautions should be done before taking and other useful information. Clonidine classification is the following: Clonidine drug class is centrally acting alpha-agonist hypotensive agents. At first, it was used as a drop in a runny nose, thanks to the spasmodic action. But very quickly they noticed the ability of it to reduce blood pressure, and then Clonidine uses changed. It became a hypotensive and sedatives meds for anxiety. The treatment of hypertension, hypertensive crises and withdrawal syndrome in drug addicts – all this is what is Clonidine used for.
Oral: -Initial dose: 0.1 mg orally 2 times a day (morning and bedtime) -Titration: Increments of 0.1 mg orally per day may be made at weekly intervals to desired response -Maintenance dose: 0.2 to 0.6 mg orally per day in divided doses -Maximum dose: 2.4 mg orally per day in divided doses Comments: -Taking the larger portion of the oral daily dose at bedtime may minimize transient adjustment effects of dry mouth and drowsiness Transdermal patches: -Initial dose: 0.1 mg/24 hr patch applied every 7 days -Maintenance dose: If, after 1 to 2 weeks the desired reduction in blood pressure is not achieved, increase the dosage by adding another 0.1 mg/24 hr patch or changing to a larger system -Maximum dose: Doses above two 0.3 mg/24 hr patches applied every 7 days is usually not associated with additional efficacy Comments: -The transdermal patch should be applied to a hairless area of intact skin on the upper outer arm or chest. -Each new patch should be applied on a different skin site from the previous location. -If the patch loosens during 7-day wearing, the adhesive cover should be applied directly over the system to ensure good adhesion. -There have been rare reports of the need for patch changes prior to 7 days to maintain blood pressure control. -When substituting patches for the oral formulation or for other antihypertensive drugs, physicians should be aware that the antihypertensive effect of the patches may not commence until 2 to 3 days after initial application; therefore, gradual reduction of prior drug dosage is advised. Some or all previous antihypertensive treatment may have to be continued, particularly in patients with more severe forms of hypertension. Use: For hypertension, alone or in combination with other antihypertensive agents Epidural infusion: -Initial dose: 30 mcg/hr as a continuous infusion -Titration: May be titrated up or down depending on pain relief and occurrence of adverse events Maximum dose 40 mcg/hr as a continuous infusion Use: For the treatment of severe pain (in combination with opiates) in cancer patients that is not adequately relieved by opioid analgesics alone. Also known as: Catapres, Kapvay The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care."I literally started this medicine 2 weeks ago and it doesn’t do anything for me. Wayyyy better for you than melatonin (which is fake news anyway).""Bipolar, ADHD mostly inattentive. I don't dare to use benzos due to addiction problems in my family. It knocks me out for a good 5 hours tops, I wake up on and off throughout the night. I want new medicine""Been on Clonidine for 2 years. Clonidine almost always puts me to sleep at dosages 37,5mg to 75mg. Only problem is that I wake up too early sometimes. Sometimes it takes 30 mins to activate, other times it take 5. I went 14 years without getting a proper nights sleep. Wish I had access to a more long-acting formula.""My daughter was using melatonin for many years to help her fall asleep due to ADHD issues. But recently it stopped working and she was up for three nights straight. Her doctor prescribed clonodine and it has been wonderful. She is no longer drowsy during the day and is doing better in school and falls asleep at night within 1/2 hour after taking the clonidine.""I've been taking this medicine since I was little (4-6 years old?
If you have it, you may experience problems falling asleep, staying asleep, or feeling unrested during the day. In your search for relief, you may have heard that clonidine can help treat insomnia. Clonidine is primarily used to treat high blood pressure (hypertension). It’s also used to treat attention deficit hyperactivity disorder (ADHD). Still, one of the side effects of clonidine is sedation, or sleepiness. Results from some clinical trials suggest that clonidine may be helpful in treating insomnia in children with ADHD, but these results are limited. Here’s what you should know about using clonidine to help you sleep. Limited studies have tested clonidine as a treatment for insomnia, and they’ve only looked at this use in children with ADHD. However, according to a meta analysis, initial studies indicated that clonidine may have helped these children fall asleep more quickly and wake up less during the night. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Sleep plays a role in development and learning processes; thus, the appropriate treatment of sleep disturbance is paramount to optimal outcomes. Listing a study does not mean it has been evaluated by the U. The empirical base for treatments to address sleep in ASD is sparse, despite wide use of pharmacologic agents such as clonidine (CLN) to target sleep disturbance. Sleep disturbance has been reported in 44-86% of children with autism spectrum disorder (ASD) and is the source of considerable stress for the affected individual and family. A randomized, controlled pilot investigation of CLN for sleep disturbance in children with ASD will allow investigators to evaluate the feasibility of conducting a much larger multisite trial to address the general lack of systematic data available to guide practitioners. Subjects will be 16 children, ages 6-14 years, inclusive, with sleep disturbance and ASD. This randomized double-blind, placebo-controlled (PBO), parallel groups study will test the efficacy of CLN following a brief sleep hygiene intervention. Outcome measures include: informant completed sleep questionnaires, daytime behavior questionnaires, and actigraphy.
Clonidine is an effective alternative to more dangerous medications for a variety of disorders. But don’t be fooled – clonidine can still be quite deadly. Clonidine is usually. Is Clonidine Effective. stimulants may not be appropriate for people with ADHD who also have sleep disorders or other.