I found this article very interesting and may help and answer few questions some members may have or have been ask for..“Clomiphene increases free testosterone levels in men with both secondary hypogonadism and erectile dysfunction: who does and does not benefit? ”Secondary hypogonadism is more common than primary gonadal failure and is seen in chronic and acute illnesses. Although testosterone has a role in erections, it’s importance in erectile dysfunction () has been controversial. Hypogonadism produced by functional suppression of pituitary gonadotropins has been shown to correct with clomiphene citrate, but with a modest effect on sexual function. We wondered if longer treatment would produce improved results. A total of 178 men with secondary hypogonadism and . For those with lower than normal age-matched levels of testosterone treatment directed at normalizing testosterone with clomiphene citrate is a viable alternative to giving androgen supplements. With the suspension of Cincinnati Reds pitcher Edinson Volquez for performance enhancing drug use and a swirl of rumors that the agent involved was clomiphene (also known as Clomid,) I thought it timely to write about how clomiphene works and how it’s used. From what I read on the internets, there is an enormous amount of misinformation floating around out there. To understand how clomiphene works, you need to know how the pituitary controls the making of testosterone in the testis. Testosterone is made by Leydig cells in the testis, which I explained in my last post. The pituitary releases a hormone called luteinizing hormone (“LH”) that stimulates the Leydig cells to make testosterone. Testosterone is converted to the female hormone estrogen, (which I also explained in my last post,) and estrogen tells the pituitary to stop making more LH. This kind of negative feedback system is common when it comes to how hormones work. As the room gets warmer, the thermostat sends less electricity to the heater.
Clomid is probably the number one fertility drug in the world. It is a relatively cheap way for most men and women struggling with hormonal fertility issues. It was widely used by women for that purpose, but then men somehow figured out it that they could use it as well. Most guys in that category who take Clomid will get a nice boost in LH, FSH and testosterone. And for some men Clomid seems to work very well: their libido goes up; their testosterone skyrockets; and they get to keep their HPT axis intact and functioning. However, as rosy as the above picture may seem, the story with Clomid is much more complex, and there is a reason that hypogonadal men tend to stick to standard testosterone therapy even though it lower fertility. (More on that later.) Because many men are now trying Clomid, one comment that I see come up on the Peak Testosterone Forum from time to time is that Clomid seems to have either a) created erectile dysfunction or b) not improved erectile strength even though total testosterone has significanly increased. Had occasional ED issues since 17, likely performance anxiety cause maturbation was always fine. Mid 30’s now and T levels were checked a few years ago and they were lower-normal. I’ve noticed ED meds really aren’t working and don’t get me fully hard anymore and after years of being a workaholic, I think maybe the idea of chlomid reset makes sense (let me know if this makes sense). Its been about two weeks, and Im guessing that since morning wood started a couple days in (which never really happened before) that my T is increasing. I was very cautious about the T converting too much to Estogen so I was taking armistane 25mg daily for a month ending the first week of chlomid (just cause I ran out currently) and 150mg daily of DIM (still taking) to control it. I am starting to wonder if my estrogen might actually be too low though, because the symptoms are anxiety, depression, lack of penis sensitivity, and ED (all of which I feel to some degree). Since I just started dating someone who I find ridiculously beautiful and even with all my ED meds (way too much, like 70mg cialis, 200mg viagra, and some levitra mixed in for good measure) I’m still not getting rock hard and I’m not feeling that much sensitivity or even excitement during sex (which I couldn’t even make happen the first week-which is when I was taking both aromatase inhibitors, but also earlier into chlomiphene. It’s not much better now either)…I want to be turned on…but I’m just not…I see that she is beautiful, but it’s like art.
People older than 65 years might be prescribed a lower dosage since they are more prone to clomid suffer from side effects. Drinking alcohol is brand not. May 12, 2016. Clomid, brand name of the drug clomiphene, is commonly prescribed to women to induce ovulation. It is also commonly used off label by men.