Breast cancer drug Tamoxifen is being used to improve the success rates in IVF for women over 40. Doctors at a British Clinic have claimed that they have used the drug to improve IVF results in women over the age of 40, having a lower ovarian reserve or limited number of eggs. Normally, women in their late 30s and 40s are offered to undergo IVF with donor eggs but if the above claims are proven to have merit, they might be able to use their own eggs for IVF. Tamoxifen given to patients after their breast cancer surgery as it helps prevent the deadly cells from growing back. However, a British clinic is using it in fertility treatments for women who are over the age of 40 and have lower egg count and perhaps, a lesser chance of getting pregnant. Professor Geeta Nargund of Create Fertility has reported that she carried out a trial by giving Tamoxifen to 31 of her patients with an average age of 40 years and a low ovarian reserve. A total of 54 IVF cycle were carried out between the women, using fresh and frozen eggs. Nargund told the British Fertility Conference in January that six of these women had successful pregnancies and became mothers. What this means is that more and more women are facing questions involving pregnancy and fertility after being diagnosed. Although this shift is causing researchers to pay more attention to these issues, it is no simple task to study pregnancy in women with breast cancer, or in women who have been treated for breast cancer. The difficulty is finding women with the same cancer status and fertility outcomes, who can be compared in randomized clinical trials. Until recently, most doctors have worried pregnancy might spark hormonal changes in breast cancer survivors that could spur the disease’s return, often counseling women against getting pregnant after they recover. Although nearly all of the studies to date have focused on small groups of women, this limited research is beginning to answer some of the most crucial questions about the safety of pregnancy for women with a personal history of breast cancer and the safety of breast cancer treatment during pregnancy. At the European Breast Cancer Conference held in March of 2010, the Royal College of Obstetricians and Gynecologists reported that pregnancy is safe for breast cancer survivors. They further advised that women should wait as long as five years after treatment before becoming pregnant.
Find out if this treatment can help increase your chances of getting pregnant. Tamoxifen produces a similar success rate of inducing ovulation in women to. However, there is insufficient data for the possible consequences of tamoxifen exposure during pregnancy. Here, we are reporting a case with inadvertent usage.