As a NYC Cosmetic Dentist, I get all manner of questions from patients. Most of them are garden variety tooth and mouth questions, but every now and again, I get a good one that I file away to post here. The other day, I got such a question that became the topic for this week's post: just why do we take certain medicines sublingually (under the tongue)? It made me pause for a second, because it's not something we think about all that often. But yes, we DO take certain medicines under our tongue. So I figured this would make an interesting topic to discuss here. And I know the one obvious answer off the top of my head -- "because then the medicine gets absorbed by the body faster" -- but then that brought up more questions like "why? Indeed, almost everyone knows the surface answer -- "the medicine is absorbed by the body faster." But why is that? essentially, when a medicine is placed under your tongue, it diffuses through the mucous membranes beneath your tongue. And because of the plethora of capillaries there, the medicine has a fairly direct route into your bloodstream. Xanax (Alprazolam) is a medication [of the benzodiazepine classification] commonly prescribed as a treatment for neuropsychiatric conditions such as: panic disorder, generalized anxiety disorder, and social anxiety disorder. On occasion, Xanax is also prescribed off-label for the management of nausea due to chemotherapy. Furthermore, Xanax is frequently pursued illicitly for the sake of recreational intoxication. In 2010, alprazolam (the generic name for Xanax) was documented as being the most prescribed and the most misused benzodiazepine in the United States. When ingested, Xanax modulates activation of GABAA receptor subunits which opens chloride ion channels to hyperpolarize neurons. As a result of neuronal hyperpolarization, the firing rates of neurons decrease, CNS activity ends up downregulated, and Xanax users may experience a combination of: anxiolytic, amnesic, anticonvulsant, hypnotic, myorelaxant, and/or sedative effects. In other words, Xanax might induce a combination of mental relaxation, physical relaxation, drowsiness, and brain fog (or cognitive impairment).
I am not sure of the moral or ethical implications of giving a person medication while they are asleep, however. If an elderly patient is asleep and you need to give them a blood pressure pill, gently put in under the tongue and it will absorb. These medications are transferred to the bloodstream from the mucous membranes in the mouth after dissolving, allowing for quick absorption that avoids the loss of potency which may come with first-pass metabolism in the stomach and liver. Preparing to Administer Sublingual Medication Administering Sublingual Medication Community Q&A13 References Sublingual medications are orally disintegrating or dissolving medications that are administered by being placed under the tongue. There are 13 references cited in this article, which can be found at the bottom of the page. from the Temple University School of Medicine in 2007. .pass_color_to_child_links a.u-margin-left--xs.u-margin-right--sm.u-padding-left--xs.u-padding-right--xs.u-absolute.u-absolute--center.u-width--100.u-flex-align-self--center.u-flex-justify--between.u-serif-font-main--regular.js-wf-loaded .u-serif-font-main--regular.amp-page .u-serif-font-main--regular.u-border-radius--ellipse.u-hover-bg--black-transparent.u-hover-bg--black-transparent:hover. Content Header .feed_item_answer_user.js-wf-loaded .
I take Xanax recreationally once in a while. I've recently acquired 6 bars and I took half of one, which did really nothing for me most likely. Alprazolam Most effective way to take xanax? I know snorting it is pointless. But will taking it sublingually or parachuting it potentiate the effects in comparison to.