Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Although there are no major human studies of prednisolone use in pregnant women, studies in several animals show that it may cause birth defects including increase cleft palate. Prednisolone should be used in pregnant women when benefits outweigh the risks and children born from mothers using prednisolone during pregnancy should be monitored for impaired adrenal function. Prednisolone is found in breast milk of mothers taking prednisolone. As a glucocorticoid, the lipophilic structure of prednisolone allows for easy passage through the cell membrane where it then binds to its respective glucocorticoid receptor (GCR) located in the cytoplasm. Upon binding, formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex to translocate inside the nucleus. Once inside the nucleus, the homodimer GC/GCR complex binds to specific DNA binding-sites known as glucocorticoid response elements (GREs) resulting in gene expression or inhibition. Complex binding to positive GREs leads to synthesis of anti-inflammatory proteins while binding to negative GREs block the transcription of inflammatory genes. If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware. If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices. Another way to prevent getting this page in the future is to use Privacy Pass. Check out the browser extension in the Chrome Store.
Ophthalmic prednisolone reduces the irritation, redness, burning, and swelling of eye inflammation caused by chemicals, heat, radiation, infection, allergy, or foreign bodies in the eye. Prednisolone is in a class of medications called steroids. It prevents swelling and redness by changing the way the immune system works. Ophthalmic prednisolone comes as a solution (liquid) and a suspension (eye drops) to instill in the eye and as an eye ointment to apply to the eye. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use prednisolone eye drops or eye ointment exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Continue to use prednisolone eye drops or eye ointment even if you feel well. Prednisolone 1% (Pred Forte®) eye drops is used to treat inflammation of the eyes caused by certain conditions. Prednisolone is a steroid medicine that is used to relieve the redness, itching, and swelling caused by eye infections and other conditions. Prednisolone 0.12% and 1% are available only with your doctor's prescription. This product is available in the following dosage forms: In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prednisolone eye drops in children. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of prednisolone eye drops in the elderly.
Prednisolone acetate 1% eye drops. Two brands of prednisolone 1% eye drops are now funded and available. The brands are Prednisolone-. Contraindications / Cautions FAQ about this section. hypersens. to drug/class/compon. ocular fungal infection; ocular viral infection; ocular mycobacterial.