Macrolide Staphylococcus aureus, Bacillus cereus, Bordetella pertussis, Chlamydia trachomatis, Corynebacterium diphtheriae, Gardnerella vaginalis, H. Macrolides produce time-dependent killing 500mg dose: Cmax: 0.4mg/L; Half-life: 35-40 hours; Volume of distribution: 23-31 L/kg; Table 3 Gastrointestinal: abdominal cramps, nausea, diarrhea, anorexia, pancreatitis Genitourinary: vulvovaginal candidiasis, renal failure Cardiovascular System: prolongation of QT interval Hepatic: hepatotoxicity, jaundice Hematologic: eosinophilia, thrombocytosis, lymphopenia Central Nervous System: headache, fatigue Endocrine/Metabolic: hyperglycemia Dermatologic: itching, nail discoloration Oral: 250mg, 600mg tablet 1gram packet 100mg/5ml, 200mg/5ml powder for reconstitution to suspension IV: 500mg vial Acute bacterial exacerbations of COPD: 500mg PO q24h x 3 days, or 500mg on day 1, 250 mg q24h on days 2-5 Acute bacterial sinusitis 500mg PO q24h x 3 days Cervicitis due to Chlamydia trachomatis: 1 gram PO x 1 dose Cervicitis due to Neisseria gonorrhoeae: 2 gram PO x 1 dose Chancroid (genital ulcer disease due to Haemophilus ducreyi): 1 gram PO x 1 Mycobacterium avium complex, prophylaxis: 1200mg PO q weekly Mycobacterium avium complex, treatment: 500 mg PO q24h (in combination with ethambutol) Pharyngitis/tonsillitis: 500mg PO day 1, then 250mg q24h on days 2-5 Community acquired pneumonia (mild severity): 500mg PO day 1, then 250mg q24h on days 2-5 Skin and skin structure infections (uncomplicated): 500mg PO day 1, 250mg q24h on days 2-5 Urethritis due to Chlamydia trachomatis: 1 gram PO x 1 Urethritis due to Neisseria gonorrhoeae: 2 gram PO x 1 Pelvic inflammatory disease: 500mg IV q24h for at least 2 days, then 250 mg PO q24h x 7 days total Community acquired pneumonia: 500mg IV q24h x at least 2 days, followed by 500mg PO q24h x 7-10 days total. influenzae, Legionella pneumophila, Moraxella catarrhalis, Mycobacterium spp., Mycoplasma pneumoniae, Pasteurella multocida, S. They impair the elongation cycle of the peptidyl chain by specifically binding to the 50 S subunit of the ribosome. These bacteria can infect the skin, nose, throat, and lungs. Clindamycin has some activity against Chlamydia trachomatis but it is inferior to azithromycin or doxycycline. It works against several different bacteria, especially chlamydia, hemophilus and streptococcus. i was told that the antibiotics may have cleared mine up could that be true ... Azithromycin is used for mild or moderate bacterial infections. Read more » Ive been on clindamycin for an infection in my mouth due to a tooth, meanwhile my boyfriend has contracted chlamidia an std. They can also be transmitted through sexual activity and cause infections in the genital area. Hi Doc, I had an episode of unprotected oral (recieved a blowjob). I would not rely on the clindamycin as adequate to treat the chlamydia that you may have contracted from your Read more » Hello Doctor Bob, this is my first post ever and I promise you that before I decided to write to you, I did a whole lot of reading of previous posts and your answers to them, but still I felt the need to ask my questions, so here goes my case: I'm a... Chlamydia can be easily treated and cured with antibiotics. The doctor prescribed me 2 grams Azithromycin 1 day after the encounter followed by 400 gms Cefixime the following day (i.e. ...would not recommend the massive doses of antibiotics! A single dose of azithromycin or a week of doxycycline (twice daily) are the most commonly used treatments. Read more » ...diseases clinic earlier this year to pick up her birth control pills. No, I would not recommend such empiric treatment for "an episode of unprotected oral." Yes, the dose of azithromycin would treat a confirmed case of Chlamydia and yes, cefixime can be used to treat resistant strains of... I am 15 years old and I have recently went to the doctors and have found out that I have been diagnosed with chlamydia. Well they told me it would only take a week to go away. Be sure to let your health care provider know about your new exposure, and as always, be safe... It's not entirely clear to me why your still having discharge, but I'd suggest going back to your doctor to be checked.
Among men can produce symptoms that cause them to seek curative treatment soon enough to prevent sequelae, but often not soon enough to prevent transmission to others. Among women, gonococcal infections are commonly asymptomatic or might not produce recognizable symptoms until complications (e.g., PID) have occurred. PID can result in tubal scarring that can lead to infertility and ectopic pregnancy. Additional risk factors for gonorrhea include inconsistent condom use among persons who are not in mutually monogamous relationships, previous or coexisting sexually transmitted infections, and exchanging sex for money or drugs. Clinicians should consider the communities they serve and might opt to consult local public health authorities for guidance on identifying groups at increased risk. Gonococcal infection, in particular, is concentrated in specific geographic locations and communities. Subgroups of MSM are at high risk for gonorrhea infection and should be screened at sites of exposure (see MSM). Screening for gonorrhea in men and older women who are at low risk for infection is not recommended ( should be performed in all persons at risk for or suspected to have gonorrhea; a specific diagnosis can potentially reduce complications, reinfections, and transmission. Azithromycin should not be used in patients with pneumonia who are judged to be inappropriate for oral therapy because of moderate to severe illness or risk factors. (1.3) To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZITHROMAX (azithromycin) and other antibacterial drugs, ZITHROMAX (azithromycin) should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. (1.4) ZITHROMAX (azithromycin) is a macrolide antibacterial drug indicated for the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below. Recommended dosages and durations of therapy in adult and pediatric patient populations vary in these indications. To reduce the development of drug-resistant bacteria and maintain the effectiveness of ZITHROMAX (azithromycin) and other antibacterial drugs, ZITHROMAX (azithromycin) should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy. After mixing, store suspension at 5° to 30°C (41° to 86°F) and use within 10 days. ZITHROMAX 250 mg tablets are supplied as pink modified capsular shaped, engraved, film-coated tablets containing azithromycin dihydrate equivalent to 250 mg of azithromycin.
Two grams of zithromax will get rid of the bacteria that caused the PID, but is not a typical, CDC approved regimen for PID. Normally you need additional coverage for pathogens that aren't covered. Adults 2 g as a single dose; consume contents of full bottle. 2.1. Each bottle of Zmax contains azithromycin dihydrate equivalent to 2 g of azithromycin.