Oral corticosteroids are used in combination with short acting beta agonists (also called bronchodilators or rescue medicines) to treat moderate to severe asthma flare-ups. Corticosteroids reduce inflammation and swelling in the airways. During an asthma attack, the inside walls of the airways swell and narrow. Reducing this swelling allows the airways to open up, allowing better air flow. Sometimes difficult-to-manage asthma can only be treated with regular use of daily or every-other-day oral corticosteroids. To treat acute asthma flare-ups, oral corticosteroids are usually prescribed in "short bursts" of five days up to two weeks. Using corticosteroids in this manner is the most effective way to reduce inflammation and the frequency of future flare-ups. Prednisone is a corticosteroid that comes in oral or liquid form. It works by acting on the immune system to help reduce the inflammation in the airways of people with asthma. Prednisone is typically given for a short period of time, like if you have to go to the emergency room or are hospitalized due to an asthma attack. Prednisone can also be given as long-term treatment if your asthma is severe or hard to control. A review article in American Journal of Medicine evaluated six different trials for adults with acute asthma episodes. In these trials, people received corticosteroid treatment within 90 minutes of arriving at the emergency room. Researchers found that these groups had lower hospital admittance rates than people who received a placebo instead. Additionally, a review on management of acute asthma attacks in American Family Physician found that people sent home with a 5- to 10-day prescription of 50 to 100 milligrams (mg) of oral prednisone had a decreased risk of relapse of asthma symptoms.
Patients with persistent asthma require medications that provide long-term control of their disease and medications that provide quick relief of symptoms. D., West Virginia University School of Medicine, Morgantown, West Virginia CHARLES D. D., West Virginia University Schools of Pharmacy and Medicine, Morgantown, West Virginia Am Fam Physician. Asthma, a common chronic inflammatory disease of the airways, may be classified as mild intermittent or mild, moderate, or severe persistent. Medications for long-term control of asthma include inhaled corticosteroids, cromolyn, nedocromil, leukotriene modifiers and long-acting bronchodilators. Inhaled corticosteroids remain the most effective anti-inflammatory medications in the treatment of asthma. Quick-relief medications include short-acting beta agonists, anticholinergics and systemic corticosteroids. The frequent use of quick-relief medications indicates poor asthma control and the need for larger doses of medications that provide long-term control of asthma. New guidelines from the National Asthma Education and Prevention Program Expert Panel II recommend an aggressive “step-care” approach. Steroids, anti-inflammatory drugs such as prednisone, can be used for asthma as well as other lung diseases. Prednisone and other steroids (inhaled, oral, or by injection) help calm airway inflammation in asthma. If you've ever had a serious asthma attack, you may have had high doses of steroids in the hospital administered intravenously. If you have serious worsening of asthma symptoms (an asthma attack), your doctor may prescribe a brief course of oral steroids such as prednisone. Oral steroids may also be prescribed when your asthma symptoms worsen but you do not require hospitalization. Oral prednisone is a systemic anti-inflammatory steroid. That means that after taking prednisone by mouth (orally), it is absorbed in the body, unlike inhaled steroids (anti-inflammatory asthma inhalers) that go straight to the lungs. Prednisone decreases your immune system's response to reduce symptoms such as swelling and allergic-type reactions.
May 13, 2016. Background People with asthma sometimes have asthma attacks, wherein their symptoms such as cough, chest tightness and difficulty. Options for adjusting medicines in a written asthma action plan for adults Opens in a new. Oral prednisone or prednisolone is rated category A for pregnancy.