Species resistant to amoxicillin, the alternatives of amoxicillin/clavulanate, clindamycin, and metronidazole need to be considered. Rastenienė et al analyzed treatment modalities and results in 1,077 patients with severe odontogenic maxillofacial infections during a 10-year period. The microbial analysis showed the highest susceptibility of predominant micro-organisms to penicillin was 76.9% and the highest resistance was to metronidazole (27.9%). This is a topical medication in which the silver acts as an antimicrobial and the fluoride promotes the remineralization of the tooth. Recommended maximum dose is one drop/25 μL per 10 kg per weekly treatment. Drug combination that extends the antibiotic spectrum of this penicillin to include bacteria normally resistant to beta-lactam antibiotics. Indicated for skin and skin structure infections caused by beta-lactamase–producing strains of Inhibits bacterial protein synthesis by inhibiting peptide chain initiation at the bacterial ribosome, where it preferentially binds to the 50S ribosomal subunit, causing bacterial growth inhibition. Most acute orofacial infections are of odontogenic origin. In normal hosts, however, they usually do not occur without some type of predisposing condition. Early recognition and management of acute orofacial infections is critical, because rapid systemic involvement can occur, especially in children. Antimicrobial therapy has an essential role in the management of these infections. If it is initiated before surgery, it can shorten the period of infection and minimize associated risks. The etiology of odontogenic infections is usually attributed to the endogenous flora of the mouth, and not to the introduction of non-resident bacteria. Odontogenic infections are typically polymicrobial; however, anaerobes generally outnumber aerobes by at least four fold.
Azithromycin Commonly Prescribed Medications in Pediatric Dentistry. and oral anaerobes to the macrolides has reduced their use in dental infections. Endodontic infections range from being asymptomatic to. PUBLISHED FOR THE DENTAL PROFESSIONAL COMMUNITY BY THE. of azithromycin. The oral.