Dear Editor: Discontinuing selective serotonin reuptake inhibitors (SSRIs) may induce a syndrome wherein the main neuropsychiatric symptoms are dizziness, shock-like sensations, anxiety, irritability, agitation, and insomnia. These symptoms usually develop 1 to 7 days after either abrupt or gradual discontinuation (13). Antidepressant discontinuation may also induce mania, mainly reported with tricyclics and monoamine oxidase inhibitors (MAOIs) but also observed with SSRIs (4). Acute psychosis has been reported in previously nonpsychotic patients following abrupt discontinuation of the MAOI phenelzine (5). Biological mechanisms may be cholinergic overdrive activating monoaminenergic systems (6) or a hyposerotonergic state arising from SSRI-induced postsynaptic serotonin receptor desensitization coupled with increased serotonin reuptake after discontinuation (7). I report the case of a patient diagnosed with bipolar disorder II (BD II, depression and hypomania alternating) according to DSM-IV criteria. This patient had a first episode of psychotic mania soon after rapid discontinuation of sertraline. Schizophrenia is usually treated with an individually tailored combination of therapy and medication. Most people with schizophrenia are treated by community mental health teams (CMHTs). The goal of the CMHT is to provide day-to-day support and treatment while ensuring you have as much independence as possible. A CMHT can be made up of and provide access to: After your first episode of schizophrenia, you should initially be referred to an early intervention team. These specialist teams provide treatment and support, and are usually made up of psychiatrists, psychologists, mental health nurses, social workers and support workers. People with complex mental health conditions are usually entered into a treatment process known as a care programme approach (CPA). A CPA is essentially a way of ensuring you receive the right treatment for your needs.
Sertraline should be discontinued in any patient entering a manic phase. Schizophrenia. Psychotic symptoms might become aggravated in schizophrenic. Zoloft sertraline generic is a prescription drug used to treat depression, obsessive-compulsive disorder, panic disorder, PTSD, social anxiety disorder, and.